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C5orf60 Knockout Cell Lines

Gene: C5orf60

Official Full Name: SPATA31 subfamily J member 1provided by HGNC

Gene Summary: Predicted to be located in membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO19252 C5orf60 Knockout cell line (HeLa) Human C5orf60 1:3~1:6 Negative Online Inquiry
KO19253 C5orf60 Knockout cell line (HCT 116) Human C5orf60 1:2~1:4 Negative Online Inquiry
KO19254 C5orf60 Knockout cell line (HEK293) Human C5orf60 1:3~1:6 Negative Online Inquiry
KO19255 C5orf60 Knockout cell line (A549) Human C5orf60 1:3~1:4 Negative Online Inquiry

Background

C5orf60 Gene Knockout Cell Lines represent a powerful tool for investigating the functional role of the C5orf60 gene, a relatively understudied entity within human genomics. These cell lines have undergone precise genetic manipulation to create a complete knockout of the C5orf60 gene, enabling researchers to elucidate its biological functions and pathways in various cellular contexts.

The primary mechanism of action relies on the CRISPR-Cas9 technology, which introduces specific double-strand breaks in the genomic DNA, followed by the cell's natural repair processes that lead to insertions or deletions (indels) causing a loss of function. This allows for the detailed study of gene-to-phenotype relationships, particularly in the context of cellular processes such as proliferation, differentiation, and response to stressors or drugs.

In terms of scientific importance, C5orf60 has been implicated in various physiological and pathological processes, making these knockout cell lines essential for researchers investigating diseases like cancer, neurodegeneration, and metabolic disorders. Their application spans basic research, drug discovery, and even translational studies aimed at understanding therapeutic targets.

Distinctively, our C5orf60 Gene Knockout Cell Lines offer significant advantages over traditional methods of gene silencing, such as RNA interference. They provide a stable and HERITABLE loss of gene expression, eliminating concerns regarding variable knockdown efficiency and off-target effects associated with RNAi techniques. Furthermore, these cell lines are rigorously validated for consistent performance across multiple experiments.

For researchers and clinicians striving to expand their understanding of gene function and its implications in health and disease, investing in our C5orf60 Gene Knockout Cell Lines not only accelerates their research endeavors but also ensures high reproducibility and validity in results. The integration of cutting-edge technologies with our product suite highlights our commitment to advancing cellular biology research. Our expertise in genetic engineering and commitment to quality makes us a trusted partner in your quest for scientific discovery and innovation.

Please note that all services are for research use only. Not intended for any clinical use.

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