Gene: C12orf57
Official Full Name: chromosome 12 open reading frame 57provided by HGNC
Gene Summary: This gene is ubiquitously expressed in human tissues. It is required for development of the human corpus callosum. Mutations in this gene are associated with Temtamy syndrome (TEMTYS). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06779 | C12orf57 Knockout cell line (HeLa) | Human | C12orf57 | 1:3~1:6 | Negative | Online Inquiry |
KO06780 | C12orf57 Knockout cell line (HCT 116) | Human | C12orf57 | 1:2~1:4 | Negative | Online Inquiry |
KO06781 | C12orf57 Knockout cell line (HEK293) | Human | C12orf57 | 1:3~1:6 | Negative | Online Inquiry |
KO06782 | C12orf57 Knockout cell line (A549) | Human | C12orf57 | 1:3~1:4 | Negative | Online Inquiry |
C12orf57 Gene Knockout Cell Lines are genetically modified cell lines in which the C12orf57 gene, implicated in various cellular processes, has been effectively disrupted. This product enables researchers to investigate the functions and molecular pathways associated with this gene by providing a model that recapitulates the absence of its normal activity.
The primary mechanism of these cell lines involves CRISPR/Cas9 technology, facilitating targeted mutations that render the C12orf57 gene inactive. By doing so, these knockout cell lines allow for the detailed analysis of gene function, including its role in cellular signaling, proliferation, and response to stressors. Researchers can utilize these models to elucidate the biological implications of C12orf57 ablation and its potential involvement in disease states, including cancer and metabolic disorders.
The scientific importance of C12orf57 Gene Knockout Cell Lines is evident in both research and clinical settings. They serve as pivotal tools for drug discovery, genetic studies, and the development of therapeutic strategies. Understanding how the loss of C12orf57 affects cellular dynamics can pave the way for innovative treatments and precision medicine approaches.
Compared to alternative gene modification methods, such as RNA interference or stable overexpression systems, our knockout cell lines provide a more permanent solution that mimics physiological gene loss. This translatability to in vivo studies is essential for obtaining reliable data that can inform future experiments and therapeutic applications.
The value of C12orf57 Gene Knockout Cell Lines to researchers and clinicians lies in their ability to enhance our understanding of gene function, driving advancements in biomedical research. The robust platform they provide allows for unparalleled exploration of C12orf57-related pathways, broadening the potential for groundbreaking discoveries.
With our company’s profound expertise in genetic engineering and a commitment to advancing biotechnological solutions, we remain a trusted partner in your research endeavors, continually offering high-quality, biologically relevant products tailored to your specific needs.
Please note that all services are for research use only. Not intended for any clinical use.
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