Gene: C12orf43
Official Full Name: chromosome 12 open reading frame 43provided by HGNC
Gene Summary: Predicted to be involved in Spemann organizer formation and negative regulation of Wnt signaling pathway. Predicted to be located in nuclear envelope. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19191 | C12orf43 Knockout cell line (HeLa) | Human | C12orf43 | 1:3~1:6 | Negative | Online Inquiry |
KO19192 | C12orf43 Knockout cell line (HCT 116) | Human | C12orf43 | 1:2~1:4 | Negative | Online Inquiry |
KO19193 | C12orf43 Knockout cell line (HEK293) | Human | C12orf43 | 1:3~1:6 | Negative | Online Inquiry |
KO19194 | C12orf43 Knockout cell line (A549) | Human | C12orf43 | 1:3~1:4 | Negative | Online Inquiry |
C12orf43 Gene Knockout Cell Lines represent a cutting-edge tool in genetic research, specifically designed to facilitate the study of the C12orf43 gene's function and its implications in various biological processes. These cell lines have been genetically engineered to lack the C12orf43 gene, allowing researchers to explore the consequences of its absence and investigate potential roles in diseases, particularly neurodegenerative disorders.
The primary mechanism underlying the functionality of these knockout cell lines lies in the intentional disruption of the C12orf43 gene, achieved through advanced CRISPR-Cas9 gene-editing technology. By creating a loss-of-function model, researchers can dissect the molecular pathways influenced by C12orf43, leading to critical insights into gene expression patterns, protein interactions, and cellular responses. This utility is especially relevant in research areas such as cellular signaling, metabolism, and the cellular response to stress, making it a versatile tool for both fundamental and applied biology.
The scientific importance of C12orf43 Gene Knockout Cell Lines extends to several domains, including neurobiology and oncology. By understanding the functional roles of this gene, scientists can uncover its contributions to diseases like amyotrophic lateral sclerosis (ALS) and other neurodegenerative conditions, paving the way for targeted therapeutic strategies.
In terms of advantages, C12orf43 Gene Knockout Cell Lines offer a highly specific, reproducible model that is tailored for translational research. Unlike alternative approaches that might rely on pharmacological inhibition or nonspecific knockdown methods, our cell lines provide a complete genetic knockout, ensuring that results are solely attributable to changes induced by C12orf43 absence. Furthermore, the ease of use and high viability of these cell lines make them suitable for both high-throughput screening and detailed mechanistic studies.
For researchers and clinicians, the availability of C12orf43 Gene Knockout Cell Lines represents a valuable resource for unraveling complex biological phenomena, developing new therapeutic options, and enhancing our understanding of genetic contributions to disease. Our company has a longstanding commitment to providing high-quality biological products and expertise, ensuring that our customers receive unparalleled support in their research endeavors. With our state-of-the-art facilities and dedication to innovation, we are uniquely positioned to contribute effectively to the field of genetic research.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.