Home / BRD1 Knockout Cell Lines

BRD1 Knockout Cell Lines

Gene: BRD1

Official Full Name: bromodomain containing 1provided by HGNC

Gene Summary: This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails. The encoded protein is a component of the MOZ/MORF acetyltransferase complex and can stimulate acetylation of histones H3 and H4, thereby potentially playing a role in gene activation. Variation in this gene is associated with schizophrenia and bipolar disorder in some study populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2017]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28963 BRD1 Knockout cell line (HeLa) Human BRD1 1:3~1:6 Negative Online Inquiry
KO28964 BRD1 Knockout cell line (HCT 116) Human BRD1 1:2~1:4 Negative Online Inquiry
KO28965 BRD1 Knockout cell line (HEK293) Human BRD1 1:3~1:6 Negative Online Inquiry
KO28966 BRD1 Knockout cell line (A549) Human BRD1 1:3~1:4 Negative Online Inquiry

Background

BRD1 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to study the function of the bromodomain containing 1 (BRD1) gene. This gene plays a critical role in various biological processes, including chromatin remodeling, gene transcription regulation, and potentially influencing neurodevelopmental pathways. Our BRD1 Gene Knockout Cell Lines are engineered to lack functional BRD1, thereby allowing researchers to investigate the phenotypic consequences of its absence, elucidate its role in cellular activities, and explore its involvement in diseases such as schizophrenia and other neuropsychiatric conditions.

The primary mechanism of our knockout cell lines revolves around targeted gene editing technologies such as CRISPR/Cas9, which enables precise disruption of the BRD1 gene. This results in loss-of-function mutations that facilitate the study of BRD1's regulatory mechanisms and interactions at both genomic and proteomic levels. The implications of utilizing these cell lines in research are substantial; they enable detailed investigations into gene function and cellular signaling pathways, providing insights that can lead to innovative therapeutic approaches.

What sets our BRD1 Gene Knockout Cell Lines apart from alternative models is their optimized design for reproducibility and robust performance in various assays. Unlike transient transfection methods, our stable knockout cell lines maintain the knockout across generations, ensuring consistent and reliable results for long-term experimental studies. Furthermore, these lines come with a complete user manual and recommended protocols, which streamline experimental design and execution.

For researchers and clinicians dedicated to understanding the complexities of gene function and neurological disorders, our BRD1 Gene Knockout Cell Lines represent a valuable asset. They not only facilitate groundbreaking discoveries in molecular biology but also contribute to the development of targeted treatments aimed at alleviating symptoms of related conditions.

This product is backed by our company’s expertise in genetic engineering and a strong commitment to advancing biomedical research. We pride ourselves on providing high-quality biological products that empower scientific progress, making us a trusted partner in the academic and clinical research communities.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.