Gene: BOLA1
Official Full Name: bolA family member 1provided by HGNC
Gene Summary: Predicted to be involved in cell redox homeostasis; intracellular iron ion homeostasis; and iron-sulfur cluster assembly. Located in mitochondrion. Part of iron-sulfur cluster assembly complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23164 | BOLA1 Knockout cell line (HeLa) | Human | BOLA1 | 1:3~1:6 | Negative | Online Inquiry |
KO23165 | BOLA1 Knockout cell line (HCT 116) | Human | BOLA1 | 1:2~1:4 | Negative | Online Inquiry |
KO23166 | BOLA1 Knockout cell line (HEK293) | Human | BOLA1 | 1:3~1:6 | Negative | Online Inquiry |
KO23167 | BOLA1 Knockout cell line (A549) | Human | BOLA1 | 1:3~1:4 | Negative | Online Inquiry |
BOLA1 Gene Knockout Cell Lines represent a significant advancement in cellular biology, created through precise gene editing techniques to specifically disrupt the BOLA1 gene. This gene is crucial for the synthesis of certain biomolecules, and its knockout allows researchers to investigate the role of BOLA1 in various biological processes, including cellular metabolism, proliferation, and stress response.
These specialized cell lines function on the premise of gene disruption via CRISPR-Cas9 technology, which creates targeted double-strand breaks in the DNA sequence. Following repair through non-homologous end joining, these modifications lead to the inactivation of the BOLA1 gene. Consequently, researchers can observe the resultant phenotypic changes and elucidate the gene's functional contributions to cellular pathways and diseases.
The scientific importance of BOLA1 Gene Knockout Cell Lines is evidenced by their applicability in both basic research and preclinical studies. They serve as invaluable tools for scientists investigating metabolic disorders, drug responses, and gene therapy approaches. In clinical settings, understanding the pathways influenced by the BOLA1 gene could facilitate new therapeutic strategies for conditions linked to this gene's dysfunction.
What sets BOLA1 Gene Knockout Cell Lines apart from similar products on the market is their high specificity and efficiency in gene editing, alongside comprehensive validation of gene knockout effectiveness through genotyping and phenotypic assessments. This ensures that the cell lines are not only reliable but also reproducible for experimental applications, providing researchers with confidence in their findings.
For researchers, clinicians, and pharmaceutical developers, these specialized cell lines offer a unique opportunity to deepen our understanding of gene function, leading to innovations in medical research and therapeutic development. The potential insights gained from utilizing BOLA1 Gene Knockout Cell Lines make them an essential addition to any laboratory focused on gene-function studies.
Our company brings extensive expertise in gene editing technologies and cellular biology, ensuring high-quality products backed by rigorous scientific validation, making us a trusted partner in advancing biological research and discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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