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BNIPL Knockout Cell Lines

Gene: BNIPL

Official Full Name: BCL2 interacting protein likeprovided by HGNC

Gene Summary: The protein encoded by this gene interacts with several other proteins, such as BCL2, ARHGAP1, MIF and GFER. It may function as a bridge molecule between BCL2 and ARHGAP1/CDC42 in promoting cell death. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO22501 BNIPL Knockout cell line (HCT 116) Human BNIPL 1:2~1:4 Negative Online Inquiry
KO22502 BNIPL Knockout cell line (HEK293) Human BNIPL 1:3~1:6 Negative Online Inquiry

Background

BNIPL Gene Knockout Cell Lines represent a groundbreaking advancement in cellular biology, designed to facilitate in-depth research on gene function and regulation. These cell lines have been specifically engineered to possess a targeted deletion of the BNIPL gene, which plays a crucial role in various biological processes including cellular proliferation, apoptosis, and stress response. The precise knockout approach utilized ensures that researchers can study the phenotype and functional impact of the absence of the BNIPL gene in a controlled environment, providing a robust platform for gathering mechanistic insights.

The primary function of BNIPL Gene Knockout Cell Lines is to enable the exploration of gene interactions and pathways associated with the BNIPL locus. By observing how the knockout affects cellular characteristics such as growth rate, signaling pathways, and response to external stimuli, researchers can uncover vital information regarding the gene's role in both physiological and pathological states. This has significant implications not only in understanding basic cellular processes but also in elucidating the molecular underpinnings of diseases, including certain cancers where BNIPL may be involved.

In terms of scientific importance, these cell lines serve as a critical tool in both fundamental research and translational studies. They can be employed in drug discovery programs aiming to identify novel therapeutic strategies, as well as in academic settings where gene function elucidation is paramount. Moreover, their use promotes reproducibility and standardization, making them an invaluable resource for scientists seeking reliable experimental results.

Compared to conventional methods such as RNA interference or CRISPR-mediated gene edits, the BNIPL Gene Knockout Cell Lines offer a more permanent and stable gene alteration that simplifies long-term experiments. This stability minimizes variability and ensures consistent results, thus enhancing the reliability of experimental outcomes. Additionally, the ease of availability and comprehensive customer support make these cell lines highly accessible to researchers at all levels.

For researchers and clinicians, the ability to manipulate key genetic pathways through our BNIPL Gene Knockout Cell Lines not only accelerates the pace of discovery but can also lead to innovative therapeutic approaches. Our company is committed to providing high-quality biological tools that empower scientists in their quest to expand our understanding of genetics and improve patient outcomes, backed by our extensive expertise in genetic engineering and cell line development.

Please note that all services are for research use only. Not intended for any clinical use.

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