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BNIP2 Knockout Cell Lines

Gene: BNIP2

Official Full Name: BCL2 interacting protein 2provided by HGNC

Gene Summary: This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38793 BNIP2 Knockout cell line (HeLa) Human BNIP2 1:3~1:6 Negative Online Inquiry
KO38794 BNIP2 Knockout cell line (HCT 116) Human BNIP2 1:2~1:4 Negative Online Inquiry
KO38795 BNIP2 Knockout cell line (HEK293) Human BNIP2 1:3~1:6 Negative Online Inquiry
KO38796 BNIP2 Knockout cell line (A549) Human BNIP2 1:3~1:4 Negative Online Inquiry

Background

BNIP2 Gene Knockout Cell Lines are specialized biological products designed to facilitate the study of the BNIP2 gene, which encodes a protein associated with various cellular processes, including apoptosis, autophagy, and cancer progression. These knockout cell lines have been meticulously engineered to lack functional BNIP2 protein, providing a crucial tool for researchers to investigate the gene's role in cellular mechanisms and pathologies.

By utilizing CRISPR-Cas9 technology, the BNIP2 Gene Knockout Cell Lines demonstrate efficient gene disruption with a high specificity, enabling scientists to explore the consequence of BNIP2 deficiency in cultured cells. The primary function of these knockout lines is to help elucidate the molecular pathways influenced by BNIP2, as well as its interactions with other cellular components. Researchers can utilize these cell lines to study alterations in cell survival, metabolic responses, and tumorigenic potential, making them applicable in both basic and applied research settings.

The importance of these cell lines cannot be overstated; they serve as the foundation for advancing our understanding of diseases related to autophagic processes, including cancer and neurodegenerative disorders. By providing robust models for experimentation, these knockout cell lines support critical investigations into therapeutic applications, such as targeted gene therapy or the development of novel oncological treatments.

Compared to alternative models, the BNIP2 Gene Knockout Cell Lines offer unmatched precision and reliability. Their specificity for the BNIP2 gene allows for clearer interpretations of experimental results, reducing the risk of off-target effects that can confound findings. This precision makes them particularly appealing for researchers who demand accurate and reproducible data.

For researchers and clinicians, the value of BNIP2 Gene Knockout Cell Lines lies in their ability to deepen our understanding of vital biological processes and their implications in human health. With access to such advanced tools, scientists can pave the way for significant discoveries in molecular biology and therapeutic strategies.

Our company stands at the forefront of biotechnology innovation, providing high-quality genetic materials and models, including the BNIP2 Gene Knockout Cell Lines, to empower researchers in their quest for scientific advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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