Gene: BLTP3B
Official Full Name: bridge-like lipid transfer protein family member 3Bprovided by HGNC
Gene Summary: Enables GARP complex binding activity; lipid transfer activity; and protein homodimerization activity. Involved in early endosome to Golgi transport and intermembrane lipid transfer. Located in cytosol and early endosome. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19410 | BLTP3B Knockout cell line (HeLa) | Human | BLTP3B | 1:3~1:6 | Negative | Online Inquiry |
KO19411 | BLTP3B Knockout cell line (HCT 116) | Human | BLTP3B | 1:2~1:4 | Negative | Online Inquiry |
KO19412 | BLTP3B Knockout cell line (HEK293) | Human | BLTP3B | 1:3~1:6 | Negative | Online Inquiry |
KO19413 | BLTP3B Knockout cell line (A549) | Human | BLTP3B | 1:3~1:4 | Negative | Online Inquiry |
BLTP3B Gene Knockout Cell Lines are genetically engineered cellular models that have had the BLTP3B gene disrupted using advanced gene-editing techniques, such as CRISPR-Cas9. These cell lines serve as essential tools for studying the biological function of the BLTP3B gene, which is implicated in various cellular processes including lipid metabolism, cell signaling pathways, and disease mechanisms. The precise knockout of this gene enables researchers to observe phenotypic changes, providing insights into its role in cellular physiology and pathology.
Functionally, the BLTP3B gene knockout methodology involves the introduction of targeted double-strand breaks in the genomic DNA, leading to error-prone repair mechanisms that effectively disrupt the gene. These knockout models can be used in a wide range of experimental setups including drug discovery, functional genomics, and the development of therapeutic strategies aimed at diseases associated with BLTP3B dysregulation.
The scientific relevance of these cell lines extends to both basic and applied research contexts. In clinical settings, understanding the mechanisms mediated by the BLTP3B gene can inform the development of innovative treatment options for metabolic disorders and other pathologies. Furthermore, these products are invaluable in toxicological studies and high-throughput screening assays, where they can offer insights into the effects of compounds on cellular behavior.
Compared to traditional cell lines, which may express differing levels of the target gene, BLTP3B Gene Knockout Cell Lines provide a uniform genetic background, ensuring reproducibility and accuracy in research outcomes. Their use reduces the variability associated with gene expression, allowing for clearer interpretation of experimental data.
Researchers and clinicians alike will find significant value in these robust cellular models, as they not only facilitate a deeper understanding of the biological roles of the BLTP3B gene but also enhance the potential for clinical applications. By utilizing these knockout cell lines, users can accelerate their research findings and improve the translational potential of their work.
Our company specializes in the development and distribution of high-quality genomic tools, leveraging years of experience and expertise in genetic engineering and cellular biology. We are committed to providing researchers with innovative and reliable products that advance scientific discovery and contribute to significant advancements in health and medicine.
Please note that all services are for research use only. Not intended for any clinical use.
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