Gene: BCAS4
Official Full Name: breast carcinoma amplified sequence 4provided by HGNC
Gene Summary: Predicted to be located in cytoplasm. Predicted to be part of BLOC-1 complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19466 | BCAS4 Knockout cell line (HeLa) | Human | BCAS4 | 1:3~1:6 | Negative | Online Inquiry |
KO19467 | BCAS4 Knockout cell line (HCT 116) | Human | BCAS4 | 1:2~1:4 | Negative | Online Inquiry |
KO19468 | BCAS4 Knockout cell line (HEK293) | Human | BCAS4 | 1:3~1:6 | Negative | Online Inquiry |
KO19469 | BCAS4 Knockout cell line (A549) | Human | BCAS4 | 1:3~1:4 | Negative | Online Inquiry |
BCAS4 Gene Knockout Cell Lines are specialized cell lines engineered to have a targeted disruption of the BCAS4 gene, which encodes the Breast Cancer Amplified Sequence 4, a protein implicated in various oncogenic processes. By employing CRISPR/Cas9 technology, these cell lines serve as invaluable tools for scientists aiming to unravel the role of BCAS4 in tumorigenesis and to study its potential as a therapeutic target.
The key function of BCAS4 Gene Knockout Cell Lines lies in their ability to facilitate loss-of-function studies, enabling researchers to investigate the biological pathways regulated by the BCAS4 gene. When the gene is knocked out, cells can be analyzed for alterations in cell proliferation, migration, and response to treatment, thereby providing insights into the molecular mechanisms driving cancer. This is particularly important in breast cancer research, where BCAS4 has been identified as a potential biomarker for progression and treatment response.
The scientific importance of these cell lines is underscored by their application in both fundamental research and translational studies. They can serve as a platform for drug discovery, enabling the testing of compounds targeting pathways influenced by BCAS4 modulation. Additionally, these knockout models can enhance the understanding of breast cancer heterogeneity and treatment resistance, thus contributing to personalized medicine approaches.
What distinguishes BCAS4 Gene Knockout Cell Lines from alternatives is their precise gene editing, consistency, and reliability in experimental outcomes. Unlike traditional methods of gene knockout, the CRISPR/Cas9 approach allows for a clean and reproducible knockout with minimal off-target effects, ensuring high-quality data. Furthermore, these cell lines are validated for a variety of assays, making them versatile for diverse applications.
For researchers and clinicians focused on advancing cancer biology, these knockout cell lines provide a powerful resource that enhances both the understanding and treatment of breast cancer. The potential to generate impactful results through these models aligns with contemporary goals in cancer research, supporting the drive towards more efficacious therapeutic strategies.
Our company specializes in the development of high-quality research tools, possessing extensive experience in gene editing technologies and cell line development. We are committed to providing researchers with innovative solutions that accelerate discovery and improve patient outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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