Gene: BARX2
Official Full Name: BARX homeobox 2provided by HGNC
Gene Summary: This gene encodes a member of the homeobox transcription factor family. A highly related protein in mouse has been shown to influence cellular processes that control cell adhesion and remodeling of the actin cytoskeleton in myoblast fusion and chondrogenesis. The encoded protein may also play a role in cancer progression. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34042 | BARX2 Knockout cell line (HEK293) | Human | BARX2 | 1:3~1:6 | Negative | Online Inquiry |
BARX2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the BARX2 gene, which plays a crucial role in various developmental and physiological processes. By utilizing CRISPR-Cas9 gene editing technology, these knockout cell lines have been meticulously crafted to provide researchers with a powerful tool to investigate the functional implications of BARX2 absence in gene regulation, cellular signaling, and disease mechanisms.
The primary function of the BARX2 gene involves the regulation of embryonic development and the maintenance of epithelial tissue homeostasis. These knockout cell lines enable the detailed study of how BARX2 influences cell proliferation, differentiation, migration, and response to external signals. This is pivotal for understanding its role in diseases such as cancer, where dysregulation of developmental pathways can lead to tumorigenesis.
In terms of scientific importance, BARX2 Gene Knockout Cell Lines can significantly advance research in fields such as developmental biology, oncology, and regenerative medicine. Their use in preclinical studies provides insight into the therapeutic targeting of pathways influenced by BARX2, enhancing drug discovery efforts and potentially leading to novel treatment approaches.
Compared to conventional genetic manipulation methods, such as RNA interference (RNAi), the BARX2 Gene Knockout Cell Lines offer permanent, stable gene disruption, allowing for long-term studies of cellular behaviors and responses. This stability is critical for producing reliable data, making these models far superior for discerning the full range of physiological and pathological roles played by the BARX2 gene.
For researchers and clinicians focused on gene function and its implications in health and disease, the BARX2 Gene Knockout Cell Lines represent an invaluable resource. Their unique capabilities facilitate innovative research approaches, yielding insights that traditional methods may not provide.
Our company specializes in providing high-quality biological products and cell lines geared towards advancing scientific discovery. With an unwavering commitment to excellence in research solutions, we ensure our offerings are tailored to meet the evolving needs of the scientific community.
Please note that all services are for research use only. Not intended for any clinical use.
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