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BAG6 Knockout Cell Lines

Gene: BAG6

Official Full Name: BAG cochaperone 6provided by HGNC

Gene Summary: This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03015 BAG6 Knockout cell line (HeLa) Human BAG6 1:3~1:6 Negative Online Inquiry
KO03016 BAG6 Knockout cell line (HCT 116) Human BAG6 1:2~1:4 Negative Online Inquiry
KO03017 BAG6 Knockout cell line (HEK293) Human BAG6 1:3~1:6 Negative Online Inquiry
KO03018 BAG6 Knockout cell line (A549) Human BAG6 1:3~1:4 Negative Online Inquiry

Background

BAG6 Gene Knockout Cell Lines are specialized cellular models designed to explore the functional role of the BAG6 gene, which is implicated in critical cellular processes such as protein quality control, apoptosis, and immune responses. By employing CRISPR/Cas9 gene-editing technology, these cell lines offer a highly efficient method for creating specific gene knockouts, allowing researchers to analyze the biological implications of BAG6 deficiency in various contexts.

The primary mechanism of action involves the targeted deletion of the BAG6 gene, resulting in the disruption of its normal regulatory functions. This knockout model enables scientists to investigate the effects on protein homeostasis, apoptotic pathways, and the cellular response to stress. Researchers can utilize these cell lines to elucidate BAG6's role in diseases such as cancer, neurodegeneration, and autoimmune disorders, enhancing our understanding of pathophysiological mechanisms.

The scientific importance of BAG6 Gene Knockout Cell Lines lies in their potential applications in both basic research and clinical settings. By studying cellular responses in these knockout models, researchers can uncover novel therapeutic targets and biomarkers that could lead to better diagnostic and treatment strategies.

What sets our BAG6 Gene Knockout Cell Lines apart from alternative products is their high purity and consistency, achieved through rigorous quality control processes. Additionally, our advanced genetic editing protocols ensure minimal off-target effects, enabling researchers to conduct reliable experiments that yield reproducible results. This level of precision is crucial for meaningful interpretations in complex biological systems.

For researchers and clinicians keen to advance their studies, using BAG6 Gene Knockout Cell Lines provides a robust tool for dissecting biological pathways and discovering new interventions. With our expertise in cellular engineering and a track record of innovation, our company is committed to providing high-quality biological products that empower the scientific community to tackle critical research questions effectively.

Please note that all services are for research use only. Not intended for any clinical use.

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