Gene: B3GLCT
Official Full Name: beta 3-glucosyltransferaseprovided by HGNC
Gene Summary: The protein encoded by this gene is a beta-1,3-glucosyltransferase that transfers glucose to O-linked fucosylglycans on thrombospondin type-1 repeats (TSRs) of several proteins. The encoded protein is a type II membrane protein. Defects in this gene are a cause of Peters-plus syndrome (PPS).[provided by RefSeq, Mar 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24081 | B3GLCT Knockout cell line (HeLa) | Human | B3GLCT | 1:3~1:6 | Negative | Online Inquiry |
KO24082 | B3GLCT Knockout cell line (HCT 116) | Human | B3GLCT | 1:2~1:4 | Negative | Online Inquiry |
KO24083 | B3GLCT Knockout cell line (HEK293) | Human | B3GLCT | 1:3~1:6 | Negative | Online Inquiry |
KO24084 | B3GLCT Knockout cell line (A549) | Human | B3GLCT | 1:3~1:4 | Negative | Online Inquiry |
B3GLCT Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the B3GLCT gene, which encodes for the enzyme β-1,3-glucosyltransferase. These knockout cell lines are generated through advanced CRISPR-Cas9 technology, allowing for precise editing of the genome to create a functional deficiency of B3GLCT. This mechanism not only enables researchers to observe the resultant phenotypic changes and pathways affected by the loss of this gene but also provides insight into its role in specific biological processes, particularly in glycosylation pathways that have implications in human health and disease.
The scientific importance of B3GLCT Gene Knockout Cell Lines lies in their potential applications in a wide array of fields, including cancer research, immunology, and metabolic disorders. By utilizing these cell lines, researchers can analyze the consequences of B3GLCT deficiency, thereby contributing to a deeper understanding of cellular mechanisms that govern various physiological and pathological states. Clinically, findings derived from these studies could inform therapeutic strategies aimed at glycosylation-related conditions.
What sets our B3GLCT Gene Knockout Cell Lines apart from alternatives in the market is their higher knockout efficiency, reproducibility, and the comprehensive validation process undergone during their development. This product offers a unique combination of purity and functional integrity, ensuring that researchers obtain consistent and reliable data.
In a landscape where precise genetic models are increasingly vital, the B3GLCT Gene Knockout Cell Lines hold immense value for researchers and clinicians alike. They enable the exploration of key questions surrounding glycobiology and can lead to groundbreaking discoveries in disease mechanisms and potential interventional strategies.
With our extensive expertise in genetic engineering and commitment to advancing research tools, our company is dedicated to providing innovative biological products that empower the scientific community to achieve their research goals efficiently and effectively.
Please note that all services are for research use only. Not intended for any clinical use.
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