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Ankrd23 Knockout Cell Lines

Gene: Ankrd23

Official Full Name: ankyrin repeat domain 23provided by RGD

Gene Summary: Predicted to enable titin binding activity and transcription cis-regulatory region binding activity. Involved in response to mechanical stimulus. Located in intercalated disc and myofibril. Biomarker of type 2 diabetes mellitus. Orthologous to human ANKRD23 (ankyrin repeat domain 23). [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO01311 Ankrd23 Knockout cell line (H9c2(2-1)) Rat Ankrd23 1:3~1:4 Negative Online Inquiry

Background

Ankrd23 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the Ankrd23 gene's functional role in various biological processes. By employing the CRISPR-Cas9 gene-editing technology, these cell lines have been successfully created to completely eliminate the expression of the Ankrd23 gene, thereby providing researchers with a valuable tool to investigate its involvement in cellular mechanisms, signaling pathways, and disease states.

The primary function of Ankrd23 Gene Knockout Cell Lines is to serve as a model for exploring the consequences of Ankrd23 deficiency on cellular physiology. The absence of this gene allows researchers to assess phenotypic changes and alterations in gene expression profiles, cellular proliferation, apoptosis, and the cellular response to stresses. Furthermore, these knockout cell lines can be instrumental in high-throughput screening applications, paving the way for potential therapeutic discoveries targeting specific pathways affected by Ankrd23.

The scientific importance of Ankrd23 Gene Knockout Cell Lines lies primarily in their application in research environments focused on muscle biology, cellular stress response, and potential links to various diseases, including cancer and muscle dystrophies. By providing insights into gene function and interaction, these cell lines contribute significantly to the understanding of complex biological systems.

Compared to traditional cell lines that may express the Ankrd23 gene, these knockout lines present advantages such as reduced background noise in experimental settings, allowing for clearer and more interpretable results. They also provide a more accurate mimicry of pathological conditions where Ankrd23 expression is altered or lost, enhancing the translational potential of research findings.

Researchers and clinicians seeking innovative solutions for their studies will find great value in Ankrd23 Gene Knockout Cell Lines as they facilitate cutting-edge research, leading to advanced knowledge and novel therapeutic strategies. Our company, with extensive expertise in genetic engineering and cell line production, is committed to delivering high-quality biological products that empower the scientific community in their quest for discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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