Gene: AZI2
Official Full Name: 5-azacytidine induced 2provided by HGNC
Gene Summary: AZI2, or NAP1, contributes to the activation of NFKB (see MIM 164011)-dependent gene expression by activating IKK-related kinases, such as NAK (TBK1; MIM 604834) (Fujita et al., 2003 [PubMed 14560022]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19513 | AZI2 Knockout cell line (HeLa) | Human | AZI2 | 1:3~1:6 | Negative | Online Inquiry |
KO19514 | AZI2 Knockout cell line (HCT 116) | Human | AZI2 | 1:2~1:4 | Negative | Online Inquiry |
KO19515 | AZI2 Knockout cell line (HEK293) | Human | AZI2 | 1:3~1:6 | Negative | Online Inquiry |
KO19516 | AZI2 Knockout cell line (A549) | Human | AZI2 | 1:3~1:4 | Negative | Online Inquiry |
AZI2 Gene Knockout Cell Lines are genetically modified cell lines specifically designed to facilitate the exploration of the AZI2 gene's biological function and its implications in various physiological contexts. Through the targeted deletion of the AZI2 gene, these knockout cell lines provide researchers with a powerful tool for investigating the pathways and processes influenced by this gene, ultimately aiding in our understanding of complex cellular responses.
The primary mechanism of function revolves around CRISPR-Cas9 technology, which enables precise editing of genomic sequences. By eliminating the AZI2 gene, these cell lines allow for the assessment of phenotypic changes, alterations in metabolic processes, and insights into cell signaling pathways that would otherwise remain obscured. This functional analysis is pivotal for elucidating the roles of AZI2 in cellular mechanisms such as apoptosis, proliferation, and differentiation.
The scientific importance of AZI2 Gene Knockout Cell Lines is particularly pronounced in research settings focused on cancer biology, metabolic disorders, and developmental biology. By providing a clear model for the investigation of gene function, these knockout lines serve as invaluable resources for discovering potential therapeutic targets or developing novel interventions in clinical settings.
In comparison to traditional gene knockdown techniques, which may provide transient effects or variable expression levels, the AZI2 gene knockout offers a stable and permanent alteration of the genome, delivering consistent and reproducible results. This stability, combined with the precision of CRISPR technology, positions AZI2 Gene Knockout Cell Lines as a superior choice for rigorous scientific inquiries.
For researchers and clinicians, these cell lines present an opportunity to generate high-quality data related to AZI2-associated pathways, ultimately contributing to advancements in biotechnology and therapeutic development. Our company is dedicated to delivering cutting-edge genetic tools and cell lines, backed by years of expertise in molecular biology and genetic engineering, ensuring that our clients have access to the most reliable and effective research products available.
Please note that all services are for research use only. Not intended for any clinical use.
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