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ASB9 Knockout Cell Lines

Gene: ASB9

Official Full Name: ankyrin repeat and SOCS box containing 9provided by HGNC

Gene Summary: This gene encodes a member of the ankyrin repeat and suppressor of cytokine signaling (SOCS) box protein family. Members of this family can interact with the elongin B-C adapter complex via their SOCS box domain and further complex with the cullin and ring box proteins to form E3 ubiquitin ligase complexes. They may function to mediate the substrate-recognition of the E3 ubiquitin ligases. A transcribed pseudogene of this gene has been identified on chromosome 15. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25625 ASB9 Knockout cell line (HeLa) Human ASB9 1:3~1:6 Negative Online Inquiry
KO25626 ASB9 Knockout cell line (HCT 116) Human ASB9 1:2~1:4 Negative Online Inquiry
KO25627 ASB9 Knockout cell line (A549) Human ASB9 1:3~1:4 Negative Online Inquiry

Background

ASB9 Gene Knockout Cell Lines are specialized cellular models engineered to lack the ASB9 gene, a critical regulator involved in various cellular processes such as signaling transduction and protein degradation. By using sophisticated gene-editing techniques such as CRISPR-Cas9, these cell lines facilitate the study of the specific functions of ASB9 in cellular physiology and pathology, allowing researchers to observe the consequences of its absence on cellular behavior and gene expression.

The primary function of ASB9 Gene Knockout Cell Lines is to enable detailed investigations into the role of ASB9 in cellular networks. These lines offer insights into its mechanisms, particularly in processes like ubiquitination and signal modulation. Researchers can utilize these models to understand disease mechanisms, particularly in cancers and metabolic disorders where ASB9 might play a pathophysiological role. In clinical settings, this knowledge can inform the development of targeted therapies, making these cell lines a valuable tool for translational research.

Compared to traditional wild-type cell lines, ASB9 Gene Knockout Cell Lines provide a unique experimental advantage by offering a controlled environment to dissect the gene's function and its interactions with other molecular pathways. This specificity allows for a more in-depth understanding of complex biological systems, reducing ambiguity in experimental outcomes. Their usage can significantly enhance the reproducibility and reliability of research findings.

For researchers and clinicians alike, the ASB9 Gene Knockout Cell Lines represent an indispensable resource that complements existing methodologies and accelerates the translation of basic research into clinical practice. By elucidating the role of ASB9, these cell lines not only contribute to fundamental biological knowledge but also aid in the quest for innovative treatment strategies.

At [Your Company Name], we specialize in providing high-quality biological products that empower researchers to push the boundaries of scientific inquiry. Our expertise in genetic engineering ensures that our ASB9 Gene Knockout Cell Lines are rigorously validated and tailored to meet the needs of today’s dynamic research environments.

Please note that all services are for research use only. Not intended for any clinical use.

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