Gene: ARSD
Official Full Name: arylsulfatase Dprovided by HGNC
Gene Summary: The protein encoded by this gene is a member of the sulfatase family. Sulfatases are essential for the correct composition of bone and cartilage matrix. The encoded protein is postranslationally glycosylated and localized to the lysosome. This gene is located within a cluster of similar arylsulfatase genes on chromosome X. A related pseudogene has been identified in the pseudoautosomal region of chromosome Y. [provided by RefSeq, Jul 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO38913 | ARSD Knockout cell line (HCT 116) | Human | ARSD | 1:2~1:4 | Negative | Online Inquiry |
KO38914 | ARSD Knockout cell line (A549) | Human | ARSD | 1:3~1:4 | Negative | Online Inquiry |
ARSD Gene Knockout Cell Lines are specialized, genetically modified cell lines designed to enable researchers to investigate the role of the Arylsulfatase D (ARSD) gene in various biological processes. This gene is involved in the degradation of sulfate esters, playing a crucial role in sulfate metabolism and signaling pathways. By utilizing these knockout cell lines, researchers can explore the biochemical pathways influenced by ARSD absence, providing insights into its implications in both normal physiology and disease states.
The primary function of ARSD Gene Knockout Cell Lines is to serve as a platform for studying gene function through the elimination of ARSD activity. This is achieved via state-of-the-art CRISPR/Cas9 gene-editing technology, ensuring precise and efficient disruption of the ARSD gene. Consequently, these cell lines allow for the assessment of phenotype changes, response to therapeutic agents, and interactions with other metabolic pathways in vitro. This mechanistic understanding is vital for elucidating the biological significance of ARSD in conditions such as metabolic disorders, neurodegenerative diseases, and cancers, where sulfate metabolism may play a pivotal role.
The scientific importance of ARSD knockout cell lines extends into both research and clinical applications. They not only enhance our fundamental understanding of gene function but also facilitate the exploration of potential gene-targeted therapies. Compared to traditional wild-type cell lines, ARSD knockout models provide a clearer representation of the biological effects attributable to the gene of interest, allowing for more robust and reproducible experimental outcomes.
What sets our ARSD Gene Knockout Cell Lines apart is their validated genetic accuracy and functional characterization, ensuring reliable experimental data. Researchers and clinicians can have confidence in using these cell lines for high-throughput screening, drug efficacy tests, and biomarker discovery.
In a landscape where precise genetic tools are paramount, our expertise in genetic engineering and cellular biology translates into high-quality, ready-to-use cell lines that expedite research and foster innovation. By choosing our ARSD Gene Knockout Cell Lines, users gain access to a powerful resource that drives advancements in understanding gene function and therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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