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ARHGAP33 Knockout Cell Lines

Gene: ARHGAP33

Official Full Name: Rho GTPase activating protein 33provided by HGNC

Gene Summary: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Alternative splice variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Feb 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO30594 ARHGAP33 Knockout cell line (HeLa) Human ARHGAP33 1:3~1:6 Negative Online Inquiry
KO30595 ARHGAP33 Knockout cell line (HCT 116) Human ARHGAP33 1:2~1:4 Negative Online Inquiry
KO30596 ARHGAP33 Knockout cell line (HEK293) Human ARHGAP33 1:3~1:6 Negative Online Inquiry
KO30597 ARHGAP33 Knockout cell line (A549) Human ARHGAP33 1:3~1:4 Negative Online Inquiry

Background

ARHGAP33 Gene Knockout Cell Lines represent a unique and innovative tool for studying the functions of the ARHGAP33 gene within cellular contexts. This product consists of genetically modified cell lines in which the ARHGAP33 gene has been knocked out, facilitating a deeper understanding of its role in key biological processes such as cell signaling, cytoskeletal dynamics, and cell migration. By eliminating ARHGAP33, researchers can investigate the consequences on cellular behaviors and pathways, providing insights that are critical for advancing knowledge in areas such as cancer biology, neurobiology, and developmental processes.

The primary function of ARHGAP33 is associated with regulating Rho GTPases, which are pivotal for cellular signaling pathways involved in various physiological responses. The knockout of this gene allows researchers to observe alterations in Rho GTPase activity, leading to modified cell morphology and motility. This mechanism provides a clear advantage for elucidating the underlying molecular mechanisms that contribute to diseases where ARHGAP33 may play a detrimental role, making these cell lines invaluable for both basic and applied research.

The scientific importance of ARHGAP33 Gene Knockout Cell Lines extends to their application in preclinical studies and drug discovery efforts. By utilizing these cell lines, researchers can assess the efficacy of potential therapeutic agents aimed at modulating Rho GTPase activity in disease models, making it possible to uncover novel treatment strategies for target conditions.

Compared to alternative methods of gene suppression, such as RNA interference, gene knockout offers a more permanent and comprehensive approach to studying gene function. Additionally, our cell lines are rigorously validated, ensuring that any experimental results are robust and reproducible, thereby enhancing the credibility of research findings.

For researchers and clinicians, the value of ARHGAP33 Gene Knockout Cell Lines lies in their ability to facilitate groundbreaking advances in understanding gene function and its implications in health and disease. By integrating these cell lines into their studies, users can pave the way for innovative discoveries that could impact clinical practices and patient outcomes.

With a strong commitment to advancing scientific exploration, our company specializes in delivering high-quality biological products tailored to meet the rigorous demands of modern research. Our expertise in genetic engineering and cell line development ensures that our offerings provide the tools needed for impactful scientific discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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