Gene: APOM
Official Full Name: apolipoprotein Mprovided by HGNC
Gene Summary: The protein encoded by this gene is an apolipoprotein and member of the lipocalin protein family. It is found associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. The encoded protein is secreted through the plasma membrane but remains membrane-bound, where it is involved in lipid transport. Alternate splicing results in both coding and non-coding variants of this gene. [provided by RefSeq, Jan 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO19762 | APOM Knockout cell line (HeLa) | Human | APOM | 1:3~1:6 | Negative | Online Inquiry |
KO19763 | APOM Knockout cell line (HCT 116) | Human | APOM | 1:2~1:4 | Negative | Online Inquiry |
KO19764 | APOM Knockout cell line (HEK293) | Human | APOM | 1:3~1:6 | Negative | Online Inquiry |
KO19765 | APOM Knockout cell line (A549) | Human | APOM | 1:3~1:4 | Negative | Online Inquiry |
APOM Gene Knockout Cell Lines represent a cutting-edge tool for investigating gene function and cellular mechanisms. These customized cell lines have been engineered using CRISPR/Cas9 technology to disable the APOM gene, which is crucial for lipid metabolism and has implications in various diseases, including cardiovascular conditions and diabetes. By creating a knockout model, researchers can study the absence of the APOM protein and its downstream effects on cellular pathways, facilitating a greater understanding of these biological processes.
The primary function of the APOM Gene Knockout Cell Lines lies in their ability to provide a controlled environment for examining gene-related alterations in metabolism and signal transduction. Through their engineered deficiencies, these lines allow for precise assessments of metabolic changes, gene expression profiles, and protein interactions, thereby enabling a thorough investigation into pathophysiological mechanisms. This innovative approach not only aids in understanding basic biological processes but also provides insights into potential therapeutic targets.
In the realm of scientific research, these cell lines are indispensable for both basic and translational studies. They can be utilized in drug discovery, genetic screening, and biochemical assays, enabling scientists to investigate therapeutic interventions aimed at APOM-related conditions. Clinically, these models hold promise for personalized medicine approaches, allowing for the identification of genetic variations that can influence patient responses to treatments.
Compared to traditional cell lines, APOM Gene Knockout Cell Lines offer superior specificity, enabling researchers to observe the direct consequences of gene deletion without confounding factors. Furthermore, their design allows for rapid and reproducible experiments, saving valuable time and resources in research workflows. This precision makes them an ideal choice over other genetic manipulation techniques.
For researchers and clinicians who seek to uncover novel insights into gene function and develop targeted therapies, the APOM Gene Knockout Cell Lines are a valuable asset. They empower scientists to forge new paths in understanding the complexities of gene regulation and disease mechanisms, ultimately contributing to improved healthcare outcomes.
Our company specializes in providing high-quality biological products, including advanced genetic models, that cater to the evolving needs of the research community. With our commitment to excellence and innovation, we are dedicated to supporting scientific exploration that drives meaningful discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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