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APBA3 Knockout Cell Lines

Gene: APBA3

Official Full Name: amyloid beta precursor protein binding family A member 3provided by HGNC

Gene Summary: The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33124 APBA3 Knockout cell line (HeLa) Human APBA3 1:3~1:6 Negative Online Inquiry
KO33125 APBA3 Knockout cell line (HCT 116) Human APBA3 1:2~1:4 Negative Online Inquiry
KO33126 APBA3 Knockout cell line (HEK293) Human APBA3 1:3~1:6 Negative Online Inquiry
KO33127 APBA3 Knockout cell line (A549) Human APBA3 1:3~1:4 Negative Online Inquiry

Background

APBA3 Gene Knockout Cell Lines represent a critical tool for researchers seeking to understand the functional implications of the APBA3 gene in various biological processes. These cell lines have been genetically engineered to permanently disable the APBA3 gene, which encodes a protein implicated in cellular signaling and synaptic function. By inhibiting APBA3, researchers can investigate its role in pathways associated with neurodegenerative diseases, memory formation, and synaptic plasticity.

The primary mechanism of action revolves around targeted gene editing technologies, often utilizing CRISPR-Cas9 or similar approaches to ensure precise knockouts of the APBA3 gene. This results in observable phenotypic changes that facilitate studies on gene function, protein interactions, and downstream signaling pathways. The resultant cell lines serve as a robust platform for assaying drug responses, elucidating disease mechanisms, and performing high-throughput screenings of therapeutic candidates.

The scientific relevance of APBA3 Gene Knockout Cell Lines is profound, particularly in the realms of neuroscience and cancer biology, where these models can lead to novel insights into disease mechanisms. Their applications extend to preclinical research, enabling the assessment of new drug compounds and shedding light on genetic contributions to complex diseases.

Unique advantages of these knockout cell lines include their stable genetic background, reproducibility in experimental setups, and flexibility in experimental design, distinguishing them from transient knockdown models or parental cell lines. Researchers can confidently rely on this product to produce consistent results across multiple experiments, enhancing the reliability of their findings.

For clinicians and researchers alike, APBA3 Gene Knockout Cell Lines not only streamline the research process but also help accelerate the translational potential of scientific discoveries into therapeutic strategies. The product stands as a testament to advances in genetic engineering that unlock new avenues in molecular and cellular biology.

Our company prides itself on its commitment to high-quality biological products, developed through rigorous scientific expertise and innovation, ensuring that our offerings remain at the forefront of research advancement.

Please note that all services are for research use only. Not intended for any clinical use.

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