Gene: ANTXR2
Official Full Name: ANTXR cell adhesion molecule 2provided by HGNC
Gene Summary: This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30420 | ANTXR2 Knockout cell line (HeLa) | Human | ANTXR2 | 1:3~1:6 | Negative | Online Inquiry |
KO30421 | ANTXR2 Knockout cell line (HCT 116) | Human | ANTXR2 | 1:2~1:4 | Negative | Online Inquiry |
KO30422 | ANTXR2 Knockout cell line (HEK293) | Human | ANTXR2 | 1:3~1:6 | Negative | Online Inquiry |
KO30423 | ANTXR2 Knockout cell line (A549) | Human | ANTXR2 | 1:3~1:4 | Negative | Online Inquiry |
ANTXR2 Gene Knockout Cell Lines are specialized biological tools designed to facilitate the study of the ANTXR2 gene's function in various cellular processes. By employing CRISPR-Cas9 gene editing technology, these cell lines have been engineered to completely disrupt the ANTXR2 expression, thereby providing a robust system for investigating the implications of its absence on cell behavior, signaling pathways, and disease progression.
The primary function of the ANTXR2 gene is to encode a receptor that plays a crucial role in mediating cellular responses to various stimuli, including interactions with pathogens and modulators of tissue inflammation. By studying these knockout lines, researchers can elucidate the mechanisms by which ANTXR2 influences processes like endocytosis, membrane trafficking, and immune responses. This is particularly significant in the context of diseases where ANTXR2 is implicated, such as certain cancers and inflammatory conditions.
In the realm of scientific research and clinical applications, ANTXR2 Gene Knockout Cell Lines serve as powerful models for drug discovery and therapeutic intervention. These models allow scientists to screen potential compounds targeting ANTXR2-related pathways, enhancing the drug development process for conditions associated with ANTXR2 dysregulation. Their importance is underscored by the increasing recognition of targeted therapies and personalized medicine, which require precise understanding of gene functions.
One key advantage of using our ANTXR2 Gene Knockout Cell Lines compared to alternatives is the high specificity and efficiency of the gene editing method employed, which minimizes off-target effects and permits reproducibility of results. Additionally, our cell lines come with comprehensive characterizations and validation data, ensuring reliability for experimental use.
For researchers and clinicians aiming to delve deeper into gene function and its implications in human health, these knockout cell lines present an invaluable resource. They enable detailed investigations that ultimately contribute to the development of innovative therapeutic strategies.
With a strong foundation in genetic research and a commitment to providing high-quality biological products, our company is dedicated to supporting cutting-edge scientific inquiries and facilitating advancements in healthcare.
Please note that all services are for research use only. Not intended for any clinical use.
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