Gene: AMBP
Official Full Name: alpha-1-microglobulin/bikunin precursorprovided by HGNC
Gene Summary: This gene encodes a complex glycoprotein secreted in plasma. The precursor is proteolytically processed into distinct functioning proteins: alpha-1-microglobulin, which belongs to the superfamily of lipocalin transport proteins and may play a role in the regulation of inflammatory processes, and bikunin, which is a urinary trypsin inhibitor belonging to the superfamily of Kunitz-type protease inhibitors and plays an important role in many physiological and pathological processes. This gene is located on chromosome 9 in a cluster of lipocalin genes. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO06349 | AMBP Knockout cell line (A549) | Human | AMBP | 1:3~1:4 | Negative | Online Inquiry |
AMBP Gene Knockout Cell Lines are engineered mammalian cell lines that have had the AMBP (Alpha-2-macroglobulin binding protein) gene inactivated through precise gene-editing techniques, such as CRISPR/Cas9. These knockout cell lines serve as critical tools in molecular biology, enabling researchers to dissect the functional roles of the AMBP gene and associated pathways in various physiological and pathological contexts.
The AMBP gene encodes for a protein involved in the regulation of several biological processes, including inflammation and tissue homeostasis. By studying AMBP gene knockout cell lines, scientists can elucidate the gene's role in cellular responses, its contributions to disease states, and uncover potential therapeutic targets. These cell lines allow for loss-of-function studies which provide insights into gene interactions within signaling pathways, making them invaluable in both academic and clinical research.
One significant advantage of AMBP Gene Knockout Cell Lines over traditional methods is their precision and reliability. Unlike pharmacological or transient transfection methods that can yield variable results, these engineered cell lines provide a consistent model for long-term studies, allowing for repeated experimentation and validation of results. Additionally, the use of knockout cell lines can streamline the screening process for identifying drug candidates that may modulate AMBP-function related pathways.
Researchers and clinicians value these cell lines for their potential applications in understanding diseases linked to AMBP, including certain cancers and metabolic disorders. By leveraging innovative techniques to create these standardized models, users can save time and resources while advancing their research objectives.
Our company prides itself on its commitment to providing high-quality, rigorously validated biological products. With our expertise in gene editing and cellular biology, we offer not only AMBP Gene Knockout Cell Lines but also a suite of complementary products, ensuring that scientists have access to the cutting-edge tools needed to drive their research forward.
Please note that all services are for research use only. Not intended for any clinical use.
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