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ALX3 Knockout Cell Lines

Gene: ALX3

Official Full Name: ALX homeobox 3provided by HGNC

Gene Summary: This gene encodes a nuclear protein with a homeobox DNA-binding domain that functions as a transcriptional regulator involved in cell-type differentiation and development. Preferential methylation of this gene's promoter is associated with advanced-stage neuroblastoma tumors. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO39018 ALX3 Knockout cell line (HEK293) Human ALX3 1:3~1:6 Negative Online Inquiry

Background

ALX3 Gene Knockout Cell Lines are specialized cell cultures that have been genetically modified to specifically inhibit the expression of the ALX3 gene. This innovative product enables researchers to study the gene's functional implications in a variety of biological processes and disease states. By employing CRISPR-Cas9 technology or similar gene-editing techniques, these cell lines facilitate the systematic investigation of ALX3's role in key cellular pathways, signaling mechanisms, and gene regulatory networks.

The primary function of the ALX3 Gene Knockout Cell Lines is to provide a model to assess the phenotypic and molecular consequences following the interruption of ALX3 gene activity. Researchers can observe changes in cell growth, differentiation, apoptosis, and other vital processes, offering essential insights into the gene's role in development and pathology. This model serves as a critical tool in elucidating the mechanisms underlying genetic diseases, cancer progression, and response to therapies.

In terms of scientific importance, these knockout cell lines are significant in both research and clinical applications. They empower scientists to conduct essential studies on the genetic underpinnings of specific conditions, potentially leading to novel therapeutic strategies. Moreover, they can also be utilized for drug screening, target validation, and biomarker discovery, enhancing our understanding of ALX3-related pathways in human disease.

Compared to alternative cell lines, ALX3 Gene Knockout Cell Lines offer unique advantages, particularly in their targeted approach to gene disruption and the availability of well-characterized backgrounds. These cell lines are rigorously validated for consistent performance, ensuring researchers achieve reproducible results. Unlike transient transfection methods, these knockout lines provide stable gene disruption, which is crucial for long-term studies and therapeutic developments.

For researchers and clinicians alike, ALX3 Gene Knockout Cell Lines represent a valuable asset in the pursuit of scientific knowledge and medical advancements. The ability to manipulate and study gene expression accurately propels forward the understanding of complex biological systems. Our company specializes in providing high-quality, innovative biological products, and with unmatched expertise in cell line development, we are dedicated to supporting the scientific community in their quest for discovery and excellence.

Please note that all services are for research use only. Not intended for any clinical use.

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