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ALPK1 Knockout Cell Lines

Gene: ALPK1

Official Full Name: alpha kinase 1provided by HGNC

Gene Summary: This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO04074 ALPK1 Knockout cell line (HeLa) Human ALPK1 1:3~1:6 Negative Online Inquiry
KO04075 ALPK1 Knockout cell line (HCT 116) Human ALPK1 1:2~1:4 Negative Online Inquiry
KO04076 ALPK1 Knockout cell line (HEK293) Human ALPK1 1:3~1:6 Negative Online Inquiry
KO04077 ALPK1 Knockout cell line (A549) Human ALPK1 1:3~1:4 Negative Online Inquiry

Background

ALPK1 Gene Knockout Cell Lines are engineered cell lines specifically designed to study the function of the ALPK1 gene, which plays a critical role in cellular signaling pathways associated with immune responses and cellular stress. These cell lines provide a unique platform for investigating the molecular mechanisms underlying various diseases, including those related to immune regulation and inflammatory responses.

The primary function of these knockout cell lines lies in their ability to facilitate the study of gene function through the intentional disruption of the ALPK1 gene. By employing CRISPR-Cas9 gene editing technology, researchers can observe the phenotype changes, alterations in signaling cascades, and the subsequent effects on cellular behavior when ALPK1 is absent. This mechanistic insight is invaluable for elucidating the gene’s role in pathophysiological processes, potentially leading to novel therapeutic targets.

Scientifically, ALPK1 Gene Knockout Cell Lines are of paramount importance in both research and clinical settings. They enable researchers to delve deep into hyper-inflammatory conditions and autoimmune diseases, providing a robust model for drug development and testing. Moreover, their applicability extends to drug discovery, toxicity testing, and the functional validation of gene therapy approaches.

Distinct from traditional cell lines, these knockout models afford researchers the unique advantage of studying the specific knockout effects of ALPK1 in a controlled environment. This high specificity allows for clear-cut data collection and analysis, leading to more reliable and reproducible results. Furthermore, our cell lines have undergone rigorous validation to ensure high efficiency and consistency.

For researchers and clinicians, the ability to gain precise insights into the ALPK1 gene’s functions can accelerate the development of innovative therapeutic strategies, thus enhancing medical outcomes. Our company has extensive expertise in genetic engineering and a commitment to delivering high-quality biological products that empower scientific discovery. With ALPK1 Gene Knockout Cell Lines, we offer an unparalleled tool for advancing the frontiers of biomedical research.

Please note that all services are for research use only. Not intended for any clinical use.

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