Gene: AFMID
Official Full Name: arylformamidaseprovided by HGNC
Gene Summary: Predicted to enable arylformamidase activity. Predicted to be involved in tryptophan catabolic process to kynurenine. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27752 | AFMID Knockout cell line (HeLa) | Human | AFMID | 1:3~1:6 | Negative | Online Inquiry |
KO27753 | AFMID Knockout cell line (HCT 116) | Human | AFMID | 1:2~1:4 | Negative | Online Inquiry |
KO27754 | AFMID Knockout cell line (HEK293) | Human | AFMID | 1:3~1:6 | Negative | Online Inquiry |
KO27755 | AFMID Knockout cell line (A549) | Human | AFMID | 1:3~1:4 | Negative | Online Inquiry |
AFMID Gene Knockout Cell Lines are specially engineered cellular models that have undergone targeted disruption of the AFMID (Aromatic L-amino acid decarboxylase, also known as L-amino acid decarboxylase) gene. This gene plays a significant role in the metabolism of essential amino acids and neurotransmitter synthesis. By utilizing CRISPR-Cas9 technology or other gene-editing approaches, these knockout cell lines provide researchers a vital tool for understanding the specific contributions of AFMID to various biological processes, including its implications in neuropharmacology and metabolic disorders.
The primary function of AFMID is to facilitate the conversion of aromatic amino acids into important metabolites, crucial for the proper functioning of neurological pathways. By studying knockout models, scientists can observe how the absence of AFMID impacts cellular behavior, signaling pathways, and ultimately, the physiological outcomes, advancing our understanding of related diseases.
The scientific importance of AFMID Gene Knockout Cell Lines extends into both fundamental and applied research contexts. They serve as valuable platforms for drug discovery, particularly in assessing the effects of novel compounds on the pathway involving AFMID-related metabolites. Moreover, their application in studying neurodegenerative diseases provides insights into potential therapeutic strategies targeting neurochemical imbalances.
Comparatively, AFMID Gene Knockout Cell Lines offer distinct advantages over traditional cell lines, such as increased specificity and a deeper understanding of gene function. Unlike commercially available options that may not encompass gene-specific effects, these knockout cell lines allow accurate modeling of disease mechanisms, leading to more reliable experimental outcomes and data reproducibility.
For researchers and clinicians focusing on metabolic and neurological research, the value of AFMID Gene Knockout Cell Lines lies in their ability to provide unprecedented insights into gene function and its consequences on health and disease. This knowledge is critical for developing targeted therapeutic approaches and personalized medicine strategies.
Our company has extensive expertise in cellular engineering and gene-editing technologies, offering a wide range of high-quality biological products tailored to meet the needs of the scientific community. Trust AFMID Gene Knockout Cell Lines to enhance your research and clinical investigations with precision and efficacy.
Please note that all services are for research use only. Not intended for any clinical use.
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