Gene: AEBP2
Official Full Name: AE binding protein 2provided by HGNC
Gene Summary: Predicted to enable DNA binding activity; metal ion binding activity; and transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Located in nucleoplasm. Part of ESC/E(Z) complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29203 | AEBP2 Knockout cell line (HeLa) | Human | AEBP2 | 1:3~1:6 | Negative | Online Inquiry |
KO29204 | AEBP2 Knockout cell line (HCT 116) | Human | AEBP2 | 1:2~1:4 | Negative | Online Inquiry |
KO29205 | AEBP2 Knockout cell line (HEK293) | Human | AEBP2 | 1:3~1:6 | Negative | Online Inquiry |
KO29206 | AEBP2 Knockout cell line (A549) | Human | AEBP2 | 1:3~1:4 | Negative | Online Inquiry |
AEBP2 Gene Knockout Cell Lines are innovative biological tools designed to facilitate the study of gene function and regulation within cellular contexts. These cell lines are derived from a process of targeted gene deletion, resulting in the ablation of the AEBP2 gene, which encodes a transcriptional regulator with significant roles in adipogenesis, inflammation, and cancer progression. The knockout mechanism allows researchers to observe the phenotypic consequences of gene loss, providing insights into cellular pathways and disease mechanisms.
The primary function of AEBP2 Gene Knockout Cell Lines lies in enabling the dissection of biological processes mediated by AEBP2. By utilizing these cell lines, researchers can investigate the downstream effects of AEBP2 deficiency, including changes in gene expression profiles, metabolic alterations, and variations in cellular behavior. This knowledge is particularly valuable in cancer research, where AEBP2 has been implicated in tumorigenesis, and in metabolic studies, particularly relating to obesity and diabetes.
From a scientific perspective, AEBP2 Gene Knockout Cell Lines are indispensable for both fundamental and applied research. In clinical settings, these models can be used to explore therapeutic strategies targeting AEBP2-related pathways, potentially aiding in the development of novel intervention strategies for obesity, metabolic disorders, and malignancies.
Compared to traditional cell lines, AEBP2 Gene Knockout Cell Lines provide a significant advantage in specificity, as they allow for the controlled study of genetic contributions without the confounding effects of other expressed alleles. This genetic precision enhances the validity of experimental outcomes and offers a clearer understanding of AEBP2 functions. Additionally, these cell lines are characterized by high reproducibility and consistent behavior, which are crucial for experimental rigor.
Given the growing importance of functional genomics in various biotechnological and medical applications, AEBP2 Gene Knockout Cell Lines represent a vital resource for researchers and clinicians seeking to elucidate complex biological questions. By leveraging our expertise in developing high-quality, genetically modified cellular models, we provide a product that not only accelerates scientific discovery but also opens new avenues for therapeutic development.
Please note that all services are for research use only. Not intended for any clinical use.
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