Home / ADCY9 Knockout Cell Lines

ADCY9 Knockout Cell Lines

Gene: ADCY9

Official Full Name: adenylate cyclase 9provided by HGNC

Gene Summary: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08796 ADCY9 Knockout cell line (HeLa) Human ADCY9 1:3~1:6 Negative Online Inquiry
KO08797 ADCY9 Knockout cell line (HCT 116) Human ADCY9 1:2~1:4 Negative Online Inquiry
KO08798 ADCY9 Knockout cell line (HEK293) Human ADCY9 1:3~1:6 Negative Online Inquiry
KO08799 ADCY9 Knockout cell line (A549) Human ADCY9 1:3~1:4 Negative Online Inquiry

Background

ADCY9 Gene Knockout Cell Lines are engineered cellular models that feature a targeted disruption of the Adenylate Cyclase 9 (ADCY9) gene, essential for the synthesis of cyclic adenosine monophosphate (cAMP), a critical second messenger involved in various signaling pathways. These cell lines enable researchers to study the effects of ADCY9 loss-of-function in areas such as neurobiology, cardiovascular health, and metabolic regulation.

The primary mechanism of these knockout cell lines revolves around the absence of ADCY9, resulting in altered cAMP levels and subsequently affecting downstream signaling events across various physiological processes. This cellular model is instrumental in elucidating the role of ADCY9 in mediating responses to extracellular signals, enhancing our understanding of diseases linked to aberrant cAMP signaling, including heart failure, obesity, and neurological disorders.

The scientific relevance of ADCY9 Gene Knockout Cell Lines is profound, particularly in research settings focused on drug development and the exploration of therapeutic targets. By using these cell lines, researchers can assess the efficacy of pharmacological agents aiming to modulate cAMP levels and examine the cascading effects on cell behavior. In clinical settings, insights gained from studies using these models can inform strategies for precision medicine, ultimately contributing to improved treatment protocols for patients with signaling pathway-related diseases.

ADCY9 Gene Knockout Cell Lines offer several advantages over traditional models, including specificity in targeting the ADCY9 gene, reproducibility of results, and the ability to quickly generate data pertinent to signaling pathways. The unique selling point lies in the certainty that these cell lines provide a clear advantage in understanding cAMP-related phenomena without the confounding factors present in other models.

For researchers and clinicians alike, investing in ADCY9 Gene Knockout Cell Lines translates to enhanced ability to explore and manipulate critical physiological processes, paving the way for innovative discoveries in the realms of health and disease management. With a strong foundation in cell line development, our company is committed to providing high-quality, characterized biological products that support cutting-edge research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.