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ADCY3 Knockout Cell Lines

Gene: ADCY3

Official Full Name: adenylate cyclase 3provided by HGNC

Gene Summary: This gene encodes adenylyl cyclase 3 which is a membrane-associated enzyme and catalyzes the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This protein appears to be widely expressed in various human tissues and may be involved in a number of physiological and pathophysiological metabolic processes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO08809 ADCY3 Knockout cell line (HeLa) Human ADCY3 1:3~1:6 Negative Online Inquiry
KO08810 ADCY3 Knockout cell line (HCT 116) Human ADCY3 1:2~1:4 Negative Online Inquiry
KO08811 ADCY3 Knockout cell line (HEK293) Human ADCY3 1:3~1:6 Negative Online Inquiry
KO08812 ADCY3 Knockout cell line (A549) Human ADCY3 1:3~1:4 Negative Online Inquiry

Background

ADCY3 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the adenylate cyclase 3 (ADCY3) gene. Adenylate cyclase enzymes play a critical role in cellular signaling by converting ATP to cyclic AMP (cAMP), a vital messenger in various physiological processes. By disrupting the ADCY3 gene, these knockout cell lines provide researchers with a unique opportunity to investigate the diverse roles of ADCY3 in cellular metabolism, signaling pathways, and behavior.

The key function of ADCY3 Gene Knockout Cell Lines lies in their ability to elucidate the biological impact of cAMP signaling through the lens of ADCY3 deficiency. Researchers can explore alterations in neurotransmitter release, neuroplasticity, and changes in hormonal responses, thereby gaining valuable insights into conditions such as obesity, anxiety, and metabolic disorders. The strategic deletion of the ADCY3 gene allows for the precise assessment of its contributions in both in vitro and in vivo models.

Scientifically, these cell lines hold significant importance in both research and clinical settings as they facilitate the understanding of how dysregulation of cAMP signaling contributes to health-related issues. The ADCY3 knockout lines serve as invaluable tools for drug discovery and therapeutic development, enabling the testing of potential ADCY3-targeted treatments for neurodegenerative diseases and psychiatric disorders.

Compared to alternative models, ADCY3 Gene Knockout Cell Lines offer higher specificity and control over experimental conditions. Unlike traditional models that may express compensatory pathways, these knockout lines provide a clear, unambiguous platform for the investigation of ADCY3 functions. This specificity enhances the reliability of research findings and reduces the potential for confounding variables.

For researchers and clinicians alike, the value of ADCY3 Gene Knockout Cell Lines lies in their ability to deepen our understanding of complex biological systems and their implications for human health. This product effectively bridges the gap between fundamental research and clinical applications, ultimately leading to better-targeted therapies and interventions.

As a leader in the development of innovative biological products, our company is committed to providing high-quality, expertly characterized cell lines that drive forward the field of biomedical research. Our ADCY3 Gene Knockout Cell Lines exemplify our dedication to advancing scientific discovery and improving patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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