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ACP1 Knockout Cell Lines

Gene: ACP1

Official Full Name: acid phosphatase 1provided by HGNC

Gene Summary: The product of this gene belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Aug 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO39128 ACP1 Knockout cell line (HeLa) Human ACP1 1:3~1:6 Negative Online Inquiry
KO39129 ACP1 Knockout cell line (HCT 116) Human ACP1 1:2~1:4 Negative Online Inquiry
KO39130 ACP1 Knockout cell line (HEK293) Human ACP1 1:3~1:6 Negative Online Inquiry
KO39131 ACP1 Knockout cell line (A549) Human ACP1 1:3~1:4 Negative Online Inquiry

Background

ACP1 Gene Knockout Cell Lines are specifically engineered cellular models that facilitate the study of the ACP1 (acid phosphatase 1) gene function through targeted gene disruption. By employing CRISPR-Cas9 technology, these cell lines provide researchers with powerful tools to investigate the implications of ACP1 in various biological processes such as signal transduction, metabolism, and cancer susceptibility. The knockout mechanism leads to a complete loss of ACP1 expression, thus enabling a comprehensive examination of the gene's role in cellular pathways.

The key function of these cell lines lies in their ability to serve as a baseline for comparative studies. Researchers can analyze phenotypic changes, gene expression, and metabolic shifts when ACP1 is absent, thereby elucidating its contribution to physiological and pathological states. This is particularly crucial as ACP1 has been implicated in diverse conditions including metabolic disorders and cancer. The precise editing capabilities of these knockout lines allow for reproducible and reliable experimental results.

In terms of scientific significance, ACP1 Gene Knockout Cell Lines are instrumental in advancing our understanding of gene function and its impact on health and disease. They are invaluable in drug discovery, toxicology studies, and the investigation of gene-environment interactions, making them an essential resource for both academic and industry researchers.

What sets these cell lines apart from other genetic models is their specificity and efficiency in gene editing, providing a higher degree of confidence in experimental outcomes. Traditional methods often result in off-target effects or incomplete gene disruption, whereas ACP1 knockout lines guarantee a robust and consistent genetic background for accurate data interpretation.

This unparalleled precision makes our product a valuable asset for researchers and clinicians, as it streamlines research processes and enhances the quality of findings related to the ACP1 gene. By choosing ACP1 Gene Knockout Cell Lines, users are not just accessing a product, but rather bridging the gap between genetic research and therapeutic innovation.

With years of expertise in developing cutting-edge biological products, our company is committed to providing exceptional tools that empower the scientific community to unlock the mysteries of gene function and advance clinical therapies.

Please note that all services are for research use only. Not intended for any clinical use.

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