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ACBD5 Knockout Cell Lines

Gene: ACBD5

Official Full Name: acyl-CoA binding domain containing 5provided by HGNC

Gene Summary: This gene encodes a member of the acyl-Coenzyme A binding protein family, known to function in the transport and distribution of long chain acyl-Coenzyme A in cells. This gene may play a role in the differentiation of megakaryocytes and formation of platelets. A related protein in yeast is involved in autophagy of peroxisomes. A mutation in this gene has been associated with autosomal dominant thrombocytopenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23458 ACBD5 Knockout cell line (HeLa) Human ACBD5 1:3~1:6 Negative Online Inquiry
KO23459 ACBD5 Knockout cell line (HCT 116) Human ACBD5 1:2~1:4 Negative Online Inquiry
KO23460 ACBD5 Knockout cell line (HEK293) Human ACBD5 1:3~1:6 Negative Online Inquiry
KO23461 ACBD5 Knockout cell line (A549) Human ACBD5 1:3~1:4 Negative Online Inquiry

Background

ACBD5 Gene Knockout Cell Lines represent a cutting-edge tool in molecular biology designed to facilitate the study of the ACBD5 gene, which encodes acyl-CoA-binding domain-containing protein 5. Gene knockout models are invaluable as they enable researchers to investigate gene function by creating organisms or cells that lack a specific gene. These specialized cell lines demonstrate a complete deletion of the ACBD5 gene, allowing for the investigation of its role in lipid metabolism and cellular signaling pathways.

The mechanism of action relies on CRISPR-Cas9 technology, which generates precise genetic modifications, ensuring specificity and efficiency in the knockout process. This level of accuracy in gene manipulation permits researchers to delineate the physiological consequences of ACBD5 deficiency, including effects on cellular growth, proliferation, and response to metabolic stresses. Additionally, the cell lines can be utilized in high-throughput screening assays to identify potential therapeutic interventions for diseases linked to ACBD5 dysregulation.

The scientific importance of these knockout cell lines extends to diverse research areas, including lipid biology, metabolic disorders, and cancer research. They can serve as invaluable models in preclinical studies, helping clinicians and researchers explore the underlying molecular mechanisms of diseases and evaluate potential treatment strategies.

What sets our ACBD5 Gene Knockout Cell Lines apart from alternatives on the market is their high-quality validation process, which confirms the efficacy and consistency of the gene knockout. Furthermore, they are produced using stringent quality control protocols, ensuring reproducibility across experiments.

By incorporating our cell lines into their research, scientists and clinicians can gain new insights into the biological roles of ACBD5, potentially leading to the development of novel therapeutic approaches. At our company, we pride ourselves on our extensive expertise in developing high-quality biological products, tailored to meet the evolving needs of the research community. With our ACBD5 Gene Knockout Cell Lines, researchers will gain an unprecedented opportunity to advance their understanding of complex biological systems.

Please note that all services are for research use only. Not intended for any clinical use.

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