Gene: ACBD3
Official Full Name: acyl-CoA binding domain containing 3provided by HGNC
Gene Summary: The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is involved in the maintenance of Golgi structure and function through its interaction with the integral membrane protein giantin. It may also be involved in the hormonal regulation of steroid formation. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20060 | ACBD3 Knockout cell line (HeLa) | Human | ACBD3 | 1:3~1:6 | Negative | Online Inquiry |
KO20061 | ACBD3 Knockout cell line (HCT 116) | Human | ACBD3 | 1:2~1:4 | Negative | Online Inquiry |
KO20062 | ACBD3 Knockout cell line (HEK293) | Human | ACBD3 | 1:3~1:6 | Negative | Online Inquiry |
KO20063 | ACBD3 Knockout cell line (A549) | Human | ACBD3 | 1:3~1:4 | Negative | Online Inquiry |
ACBD3 Gene Knockout Cell Lines are engineered cellular models that lack the expression of the ACBD3 gene, a key regulator involved in intracellular transport and membrane trafficking. These cell lines are derived through advanced CRISPR-Cas9 gene-editing technology, an approach that allows for precise modification of genomic sequences, ensuring that the resultant lines exhibit a complete knockout of ACBD3 with minimal off-target effects.
The primary function of ACBD3 is to facilitate the transport of proteins and lipids within the cell, and its loss leads to significant alterations in cellular homeostasis and communication. By utilizing ACBD3 knockout cell lines, researchers can dissect the pathways affected by the absence of this gene, leading to insights into cellular processes such as autophagy, endocytosis, and viral entry mechanisms. These models serve as vital tools for studying diseases related to dysregulated membrane trafficking and may also contribute to the development of therapeutic strategies targeting related pathways.
The scientific importance of ACBD3 Gene Knockout Cell Lines lies in their application in both basic research and clinical settings. They enable in-depth studies on the impact of ACBD3 on cellular functions, potentially revealing novel biomarkers or therapeutic targets for diseases like cancer, neurodegeneration, and infectious diseases. Furthermore, the accurate modeling of these conditions provides highly relevant contexts for drug testing and the evaluation of therapeutic interventions.
What sets our ACBD3 Gene Knockout Cell Lines apart from alternative products is their rigorous validation and characterization, ensuring consistent performance across experiments. These cell lines are generated and maintained under stringent quality control measures, providing researchers with reliable and reproducible results.
Investing in ACBD3 Gene Knockout Cell Lines empowers researchers and clinicians to explore innovative biological inquiries and advance their understanding of complex disease mechanisms. This product is a testament to our company's commitment to pioneering solutions in basic and translational research, backed by expertise in gene editing and cell line development. Our mission is to enable scientific progress with high-quality, reliable tools that lead to meaningful discoveries in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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