Gene: ACAP2
Official Full Name: ArfGAP with coiled-coil, ankyrin repeat and PH domains 2provided by HGNC
Gene Summary: Enables GTPase activator activity. Acts upstream of or within actin filament-based process. Located in ruffle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO29195 | ACAP2 Knockout cell line (HeLa) | Human | ACAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO29196 | ACAP2 Knockout cell line (HCT 116) | Human | ACAP2 | 1:2~1:4 | Negative | Online Inquiry |
KO29197 | ACAP2 Knockout cell line (HEK293) | Human | ACAP2 | 1:3~1:6 | Negative | Online Inquiry |
KO29198 | ACAP2 Knockout cell line (A549) | Human | ACAP2 | 1:3~1:4 | Negative | Online Inquiry |
ACAP2 Gene Knockout Cell Lines are genetically engineered cellular models that lack the expression of the ACAP2 gene, a crucial element involved in endocytosis and vesicle trafficking. These knockout models are essential for elucidating the biological functions of ACAP2 in various cellular processes, including signal transduction, protein recycling, and membrane dynamics. By eliminating this specific gene, researchers can assess not only the contributions of ACAP2 to normal cellular physiology but also its implications in disease states, including cancer and neurodegeneration.
The primary mechanism of action involves the strategic use of techniques such as CRISPR/Cas9 or RNA interference, which allow for precise editing of the genome. This results in a permanent loss of ACAP2 function, facilitating detailed studies on downstream signaling pathways and the role of ACAP2 in cellular responses. The availability of these knockout cell lines paves the way for in-depth research into potential therapeutic targets, enabling scientists to uncover new avenues for drug discovery and biotechnological applications.
The scientific significance of ACAP2 Gene Knockout Cell Lines extends to both academic and clinical research settings. They serve as invaluable tools for studying disease mechanisms, drug interactions, and new therapeutic strategies. Furthermore, researchers have observed that utilizing knockout models can yield more robust data compared to wild-type counterparts, allowing for more reliable interpretation of the gene's function.
What sets our ACAP2 Gene Knockout Cell Lines apart from alternatives is their superior specificity and reliability. Each cell line undergoes rigorous validation to ensure complete knockout of the ACAP2 gene without off-target effects, making them highly dependable for experiments requiring precise genetic manipulation. Additionally, our commitment to quality control means these cell lines are continuously tested for functionality and stability, ensuring consistent research outcomes.
For researchers and clinicians, the value of using ACAP2 Gene Knockout Cell Lines lies in their potential to advance understanding of critical cellular processes and their applications in unraveling complex disease mechanisms. With our expertise in producing high-quality biological products, we are dedicated to supporting the scientific community by providing tools that enable groundbreaking research and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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