Gene: ABTB1
Official Full Name: ankyrin repeat and BTB domain containing 1provided by HGNC
Gene Summary: This gene encodes a protein with an ankyrin repeat region and two BTB/POZ domains, which are thought to be involved in protein-protein interactions. Expression of this gene is activated by the phosphatase and tensin homolog, a tumor suppressor. Alternate splicing results in three transcript variants. [provided by RefSeq, Mar 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25995 | ABTB1 Knockout cell line (HeLa) | Human | ABTB1 | 1:3~1:6 | Negative | Online Inquiry |
KO25996 | ABTB1 Knockout cell line (HCT 116) | Human | ABTB1 | 1:2~1:4 | Negative | Online Inquiry |
KO25997 | ABTB1 Knockout cell line (HEK293) | Human | ABTB1 | 1:3~1:6 | Negative | Online Inquiry |
KO25998 | ABTB1 Knockout cell line (A549) | Human | ABTB1 | 1:3~1:4 | Negative | Online Inquiry |
ABTB1 Gene Knockout Cell Lines are specially engineered cellular models that facilitate the study of the ABTB1 gene's function and its role in various biological processes. These cell lines have undergone targeted gene editing techniques, such as CRISPR/Cas9, to effectively disrupt the ABTB1 gene, allowing researchers to investigate the resulting phenotypic changes. By comparing knockout cells to their wild-type counterparts, researchers can elucidate the gene's involvement in cellular pathways, signaling mechanisms, and potential disease processes.
The primary function of ABTB1 knockout cell lines is to provide a valuable tool for understanding the physiological and pathological roles of ABTB1 in specific biological contexts, including cancer biology, immune response, and neurodegeneration. The disruption of this gene impacts cellular behaviors such as proliferation, differentiation, and apoptosis, thereby shedding light on the gene's relevance in both health and disease.
In scientific research, ABTB1 knockout cell lines serve critical roles in drug discovery and development, as they enable the screening of therapeutic compounds targeting pathways associated with ABTB1 function. Clinically, these cell lines can help identify biomarkers for disease progression and treatment efficacy, enhancing personalized medicine approaches.
One of the distinct advantages of utilizing ABTB1 knockout cell lines lies in their specificity and reproducibility. Unlike conventional methods that rely on pharmacological inhibitors or RNA interference, which often produce non-specific effects, these knockout models offer precise genetic modification. This specificity translates into reliable data, enabling researchers to draw meaningful conclusions about ABTB1's role.
As a trusted provider of high-quality biological products, our company prides itself on delivering expertly engineered gene knockout cell lines that adhere to rigorous standards of quality and reproducibility. Our commitment to advancing scientific discovery ensures that researchers, clinicians, and biopharma companies can rely on our products to propel their investigations and therapeutic developments. With ABTB1 Gene Knockout Cell Lines, you gain a pivotal resource for unraveling the complexities of gene function in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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