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RUNX3 Knockout cell line (HEK293)

Catalog Number: KO38683

Price: Online Inquiry

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Specifications

Product Information
Product Name RUNX3 Knockout cell line (HEK293)
specification 1*10^6
Storage and transportation Dry ice preservation/T25 live cell transportation.
Cell morphology Epithelioid, adherent cell
Passage ratio 1:3~1:6
species Human
Gene RUNX3
Gene ID 864
Build method Electric rotation method / virus method
Mycoplasma testing Negative
Cultivation system 90%DMEM+10% FBS
Parental Cell Line HEK293
Quality Control Genotype: RUNX3 Knockout cell line (HEK293) >95% viability before freezing. All cells were tested and found to be free of bacterial, viruses,mycoplasma and other toxins.
Gene Information
Gene Official Full Name RUNX family transcription factor 3provided by HGNC
Also known as AML2; CBFA3; PEBP2aC
Gene Description This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Expression Biased expression in bone marrow (RPKM 19.5), spleen (RPKM 16.7) and 12 other tissues See more

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