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ZWINT Knockout Cell Lines

Gene: ZWINT

Official Full Name: ZW10 interacting kinetochore proteinprovided by HGNC

Gene Summary: This gene encodes a protein that is clearly involved in kinetochore function although an exact role is not known. It interacts with ZW10, another kinetochore protein, possibly regulating the association between ZW10 and kinetochores. The encoded protein localizes to prophase kinetochores before ZW10 does and it remains detectable on the kinetochore until late anaphase. It has a uniform distribution in the cytoplasm of interphase cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02810 ZWINT Knockout cell line (HeLa) Human ZWINT 1:3~1:6 Negative Online Inquiry
KO02811 ZWINT Knockout cell line (HCT 116) Human ZWINT 1:2~1:4 Negative Online Inquiry
KO02812 ZWINT Knockout cell line (HEK293) Human ZWINT 1:3~1:6 Negative Online Inquiry

Background

ZWINT Gene Knockout Cell Lines are expertly engineered cellular models that permanently disable the ZWINT gene, which encodes a protein critical for various cellular processes, including cell division and chromosomal stability. These cell lines are meticulously developed using CRISPR-Cas9 technology, a pioneering gene-editing method that provides unprecedented precision in targeting specific genes. By knocking out the ZWINT gene, researchers can investigate the molecular pathways and phenotypic consequences of its absence, advancing our understanding of its role in cellular mechanisms.

The primary function of ZWINT Gene Knockout Cell Lines lies in their ability to serve as robust platforms for functional studies. This knockout approach allows scientists to dissect the role of the ZWINT protein in apoptosis, tumorigenesis, and other critical cellular functions. Moreover, these cell lines are valuable for screening potential therapeutic compounds that target the pathways influenced by ZWINT, providing insights that could lead to novel treatments in oncology and beyond.

In the realm of scientific research and clinical applications, the importance of ZWINT knockout models cannot be overstated. They provide a reliable framework for studying diseases that have been linked to aberrations in cell division and genomic integrity, thereby facilitating the development of targeted therapies. Furthermore, they offer a more relevant in vitro environment compared to traditional, non-specific cell models.

ZWINT Gene Knockout Cell Lines stand out against alternatives due to their high specificity, reproducibility, and the comprehensive validation they undergo prior to release. In addition, the cells come with detailed characterization data, ensuring that users can confidently utilize them in their studies.

For researchers and clinicians aiming to unlock the underlying mechanisms of diseases related to the ZWINT gene, this product presents an invaluable tool. Its robust design allows for a myriad of applications, enhancing experimental outcomes and supporting innovative research strategies.

As a leader in the field of genetic engineering and biotechnology, our company combines extensive expertise with a commitment to delivering high-quality biological products. We are dedicated to providing researchers with the tools they need to advance science and improve patient care.

Please note that all services are for research use only. Not intended for any clinical use.

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