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ZNF879 Knockout Cell Lines

Gene: ZNF879

Official Full Name: zinc finger protein 879provided by HGNC

Gene Summary: This gene encodes a kruppel-associated box-containing zinc finger protein (KRAB-ZFP). The encoded protein contains an N-terminal kruppel-associated box (KRAB) domain and thirteen C-terminal C2H2-type zinc finger domains. The KRAB-ZFPs represent the largest family of mammalian transcriptional repressors, which function through the recruitment of the nuclear co-factor KRAB-Associated Protein 1 (KAP1), to engage histone modifiers and induce heterochromatin formation. [provided by RefSeq, Jul 2017]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11911 ZNF879 Knockout cell line (HeLa) Human ZNF879 1:3~1:6 Negative Online Inquiry
KO11912 ZNF879 Knockout cell line (A549) Human ZNF879 1:3~1:4 Negative Online Inquiry

Background

ZNF879 Gene Knockout Cell Lines are specialized cell models engineered to lack the expression of the ZNF879 gene, part of the zinc finger protein family involved in various cellular processes, including transcriptional regulation and DNA repair. This technologically advanced product is created through precise gene-editing techniques, such as CRISPR-Cas9, ensuring the elimination of ZNF879 function with high specificity and efficiency.

The primary function of ZNF879 Gene Knockout Cell Lines is to provide researchers with a valuable in vitro model to study the loss-of-function effects of the ZNF879 gene. These cell lines facilitate the investigation of its involvement in critical pathways related to cell proliferation, differentiation, and apoptosis, thereby offering insights into various diseases, including cancers and genetic disorders. By examining the biological consequences of ZNF879 deletion, researchers can uncover potential therapeutic targets and elucidate pathogenic mechanisms.

The scientific importance of these cell lines cannot be overstated, as they enable advanced research applications in drug discovery, functional genomics, and personalized medicine. Their specific utility in cancer research, for example, helps scientists identify new biomarkers and treatment strategies by simulating real-life genetic scenarios without the complications associated with in vivo studies.

Compared to traditional cell lines or non-targeted genetic models, ZNF879 Gene Knockout Cell Lines stand out for their precision and reproducibility. They yield consistent results, which are paramount for validation experiments and subsequent hypothesis-driven studies. The elimination of off-target effects inherent in earlier gene-editing methodologies enhances their suitability for high-throughput screening and mechanistic studies.

For researchers and clinicians, the value of ZNF879 Gene Knockout Cell Lines lies in their ability to streamline experimental workflows while providing robust, interpretable data. With these models, users can advance their understanding of gene function and its implications in health and disease with confidence.

At [Your Company Name], we specialize in the development of high-quality genetic models, leveraging cutting-edge technologies to meet the evolving needs of the scientific community. Our expertise ensures that you receive products engineered to the highest standards, empowering your research and clinical endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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