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ZNF684 Knockout Cell Lines

Gene: ZNF684

Official Full Name: zinc finger protein 684provided by HGNC

Gene Summary: Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within innate immune response and negative regulation of single stranded viral RNA replication via double stranded DNA intermediate. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27064 ZNF684 Knockout cell line (HeLa) Human ZNF684 1:3~1:6 Negative Online Inquiry
KO27065 ZNF684 Knockout cell line (HCT 116) Human ZNF684 1:2~1:4 Negative Online Inquiry
KO27066 ZNF684 Knockout cell line (HEK293) Human ZNF684 1:3~1:6 Negative Online Inquiry
KO27067 ZNF684 Knockout cell line (A549) Human ZNF684 1:3~1:4 Negative Online Inquiry

Background

ZNF684 Gene Knockout Cell Lines are genetically engineered cell lines in which the ZNF684 (Zinc Finger Protein 684) gene has been deliberately inactivated or "knocked out." This innovative tool is crucial for studying the functional role of the ZNF684 gene, which is implicated in various biological processes and diseases, including cancer and developmental disorders. By utilizing CRISPR/Cas9 technology or other gene-editing techniques, the knockout cell lines allow researchers to observe the phenotypic consequences of ZNF684 gene disruption in a controlled environment.

The primary function of ZNF684 knockouts is to provide insights into gene function and regulation. Researchers can investigate the effects of ZNF684 on cellular processes such as proliferation, differentiation, and apoptosis. By creating a model that mimics the genetic landscape of specific diseases, these cell lines serve as platforms for drug screening, pathway analysis, and biomarker discovery. Importantly, the knockout model enables the dissection of genetic interactions and helps identify potential therapeutic targets.

The scientific importance of ZNF684 Gene Knockout Cell Lines extends to both research and clinical settings. They empower researchers to develop a deeper understanding of the molecular mechanisms underlying diseases associated with ZNF684 dysregulation. Moreover, these cell lines can inform therapeutic strategies by allowing the evaluation of pharmacologic interventions and genetic compensatory mechanisms.

Compared to alternative methods of gene functional analysis, such as overexpression studies or wild-type models, ZNF684 knockouts offer the distinct advantage of providing a clearer understanding of loss-of-function phenotypes. This specificity enables precise characterization of gene function, facilitating more robust experimental outcomes.

For researchers and clinicians, the value of ZNF684 Gene Knockout Cell Lines lies in their ability to illuminate complex biological pathways and disease mechanisms. By providing a versatile and reliable model system, these cell lines are an invaluable resource for advancing genetic research and therapeutic discovery.

With extensive expertise in genetic engineering and cell line development, our company is dedicated to providing high-quality biological products that support the scientific community in unraveling the complexities of gene function and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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