Gene: ZNF674
Official Full Name: zinc finger protein 674provided by HGNC
Gene Summary: This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked cognitive disabilities. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12074 | ZNF674 Knockout cell line (HeLa) | Human | ZNF674 | 1:3~1:6 | Negative | Online Inquiry |
KO12075 | ZNF674 Knockout cell line (HCT 116) | Human | ZNF674 | 1:2~1:4 | Negative | Online Inquiry |
KO12076 | ZNF674 Knockout cell line (HEK293) | Human | ZNF674 | 1:3~1:6 | Negative | Online Inquiry |
KO12077 | ZNF674 Knockout cell line (A549) | Human | ZNF674 | 1:3~1:4 | Negative | Online Inquiry |
ZNF674 Gene Knockout Cell Lines are innovative biological tools that enable researchers to study the functional role of the ZNF674 gene by selectively disrupting its expression. These cell lines are engineered using CRISPR/Cas9 technology, which utilizes a guide RNA to target and introduce double-strand breaks in the genomic DNA at specific sites of the ZNF674 gene. This precise editing technique results in a complete knockout of gene expression, allowing for in-depth analysis of ZNF674’s function in various biological processes, such as cellular differentiation, gene regulation, and response to environmental stimuli.
The primary function of these knockout cell lines is to provide a reliable model for exploring the implications of the ZNF674 gene in both physiological and pathological contexts. By studying these cell lines, researchers can decipher the gene's role in diseases such as cancer, neurological disorders, and other conditions where ZNF674 may exert significant effects. The development and application of ZNF674 knockout models can facilitate drug discovery, genetic research, and therapeutic strategy formulation.
One of the unique advantages of ZNF674 Gene Knockout Cell Lines is their specificity and efficiency in gene disruption compared to alternative knockout methods such as RNA interference, which often leads to incomplete knockdown and off-target effects. Moreover, these knockout lines are rigorously validated, ensuring consistent and reproducible results across experiments.
These cell lines offer researchers and clinicians a powerful tool to investigate gene function with accuracy and clarity, ultimately advancing our understanding of gene-regulatory networks and disease mechanisms. With a commitment to quality and innovation, our company specializes in the development of high-fidelity biological tools that empower scientific discovery and contribute to advancements in medical research and clinical applications.
Please note that all services are for research use only. Not intended for any clinical use.
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