Gene: ZNF598
Official Full Name: zinc finger protein 598, E3 ubiquitin ligaseprovided by HGNC
Gene Summary: Zinc-finger proteins bind nucleic acids and play important roles in various cellular functions, including cell proliferation, differentiation, and apoptosis. This protein and Grb10-interacting GYF protein 2 have been identified as a components of the mammalian 4EHP (m4EHP) complex. The complex is thought to function as a translation repressor in embryonic development. [provided by RefSeq, Oct 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23627 | ZNF598 Knockout cell line (HeLa) | Human | ZNF598 | 1:3~1:6 | Negative | Online Inquiry |
KO23628 | ZNF598 Knockout cell line (HCT 116) | Human | ZNF598 | 1:2~1:4 | Negative | Online Inquiry |
KO23629 | ZNF598 Knockout cell line (HEK293) | Human | ZNF598 | 1:3~1:6 | Negative | Online Inquiry |
KO23630 | ZNF598 Knockout cell line (A549) | Human | ZNF598 | 1:3~1:4 | Negative | Online Inquiry |
ZNF598 Gene Knockout Cell Lines represent a powerful tool in genetic and cellular research. These cell lines have been specifically engineered to lack the ZNF598 gene, which is essential for various cellular processes, including the regulation of protein synthesis and the response to ribosomal stress. By knocking out this gene, researchers can investigate the role of ZNF598 in cellular function and disease progression, facilitating a deeper understanding of gene regulation and expression mechanisms.
The primary mechanism through which ZNF598 influences cellular activity involves its role as a transcriptional regulator of stress response pathways. Mutations or deletions of ZNF598 have been implicated in diverse pathologies, such as cancer and neurodegenerative disorders, making the knockout cell lines invaluable for studies aimed at elucidating the molecular underpinnings of these conditions. Furthermore, they serve as a model to assess potential therapeutic targets that could modify the cellular responses mediated by the ZNF598 pathway.
In comparison to alternative gene knockout models, ZNF598 Gene Knockout Cell Lines offer specific advantages, including their high reproducibility and the ability to quickly generate isogenic cells for comparative studies. This can significantly enhance the reliability of experimental outcomes, especially when assessing drug responses or genetic interactions.
Researchers and clinicians will find immense value in employing these cell lines to validate experimental hypotheses, explore gene therapy approaches, or develop novel treatments that modulate the consequences of ZNF598 loss. With the growing emphasis on precision medicine, gaining insights from these knockout models becomes essential.
Our company specializes in cutting-edge biotechnology solutions and maintains a strong commitment to supporting the scientific community with advanced offerings like ZNF598 Gene Knockout Cell Lines that facilitate innovative research and therapeutic exploration.
Please note that all services are for research use only. Not intended for any clinical use.
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