Gene: ZNF445
Official Full Name: zinc finger protein 445provided by HGNC
Gene Summary: Enables double-stranded methylated DNA binding activity. Involved in epigenetic programing of female pronucleus and negative regulation of gene expression via chromosomal CpG island methylation. Located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12223 | ZNF445 Knockout cell line (HeLa) | Human | ZNF445 | 1:3~1:6 | Negative | Online Inquiry |
KO12224 | ZNF445 Knockout cell line (HCT 116) | Human | ZNF445 | 1:2~1:4 | Negative | Online Inquiry |
KO12225 | ZNF445 Knockout cell line (HEK293) | Human | ZNF445 | 1:3~1:6 | Negative | Online Inquiry |
KO12226 | ZNF445 Knockout cell line (A549) | Human | ZNF445 | 1:3~1:4 | Negative | Online Inquiry |
ZNF445 Gene Knockout Cell Lines represent a sophisticated tool for researchers investigating the role of the ZNF445 gene, which encodes a zinc-finger protein with implications in gene regulation and cellular differentiation. These engineered cell lines have undergone targeted genetic modification to completely ablate the expression of the ZNF445 gene, allowing scientists to explore loss-of-function phenotypes and uncover the biological pathways influenced by this critical gene.
The key functions of these knockout cell lines lie in their ability to facilitate the study of ZNF445’s contributions to various cellular processes, such as transcriptional regulation, cell cycle progression, and response to environmental stressors. By utilizing CRISPR/Cas9 or other nucleic acid manipulation techniques, the ZNF445 Gene Knockout Cell Lines serve as a model to elucidate the complex interactions within gene networks, providing insights into potential regulatory mechanisms at play in both normal and pathological states.
The scientific importance of this product is significant in both research and clinical settings, particularly in the fields of cancer biology, developmental biology, and regenerative medicine. Understanding ZNF445's function could lead to novel therapeutic targets or biomarkers, enhancing the precision of treatment strategies for diseases associated with dysregulated gene expression.
One key advantage of ZNF445 Gene Knockout Cell Lines is their specificity and reproducibility compared to other methods, such as pharmacological inhibition or transient RNA interference. This specificity facilitates more accurate interpretations of experimental outcomes, minimizing off-target effects that can obscure biological insights. Additionally, these cell lines are designed for ease of use and integration into existing workflows, making them accessible for laboratories of varying scales and expertise.
For researchers and clinicians seeking to deepen their understanding of gene function and its implications in health and disease, ZNF445 Gene Knockout Cell Lines offer an invaluable resource. By providing a foundational system to dissect the role of ZNF445, these cell lines can accelerate innovative discoveries and clinical applications alike.
Our company specializes in producing high-quality genetic models, leveraging advanced technologies and a commitment to scientific excellence. We pride ourselves on equipping the research community with precise tools that drive forward our understanding of genetics and its wide-ranging effects on life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.