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ZNF438 Knockout Cell Lines

Gene: ZNF438

Official Full Name: zinc finger protein 438provided by HGNC

Gene Summary: Enables DNA-binding transcription factor activity. Involved in negative regulation of DNA-templated transcription. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27596 ZNF438 Knockout cell line (HeLa) Human ZNF438 1:3~1:6 Negative Online Inquiry
KO27597 ZNF438 Knockout cell line (HCT 116) Human ZNF438 1:2~1:4 Negative Online Inquiry
KO27598 ZNF438 Knockout cell line (HEK293) Human ZNF438 1:3~1:6 Negative Online Inquiry
KO27599 ZNF438 Knockout cell line (A549) Human ZNF438 1:3~1:4 Negative Online Inquiry

Background

ZNF438 Gene Knockout Cell Lines represent a pivotal advancement in cellular research and gene function studies. These specialized cell lines have undergone targeted gene editing to entirely disrupt the ZNF438 gene, a member of the zinc finger protein family implicated in various biological processes, including transcriptional regulation and development. By manipulating this critical gene, researchers can investigate its roles in cellular pathways, disease mechanisms, and potential therapeutic targets, fostering a deeper understanding of molecular biology.

The key function of ZNF438 Gene Knockout Cell Lines lies in their ability to serve as robust models for studying gene function and interaction. Knockout technology, primarily facilitated by CRISPR/Cas9 or similar gene-editing strategies, effectively creates a loss-of-function model, enabling scientists to observe phenotypic changes, assess downstream signaling pathways, and delineate the gene’s involvement in health and disease. This allows for not only fundamental biological insights but also promises translation into therapeutic applications, including drug discovery and disease modeling.

The scientific importance of these cell lines cannot be overstated; they are valuable tools in both research and clinical settings. Their applications range from basic cellular and molecular biology studies to advanced applications such as cancer research, neurobiology, and understanding genetic disorders. Researchers can utilize ZNF438 knockout models to uncover the underlying mechanisms of disease, potentially leading to innovative treatment strategies.

In comparison to alternative models, ZNF438 Gene Knockout Cell Lines offer a high specificity in targeting the ZNF438 gene without off-target effects, ensuring that the resulting data is both reliable and reproducible. These cell lines have been validated for consistency and efficiency and provide a standardized platform that accelerates research timelines.

For researchers and clinicians, the ZNF438 Gene Knockout Cell Lines present a unique value proposition: they enable in-depth exploration of a gene’s function in a controlled environment, facilitating breakthroughs in understanding and therapeutics. Additionally, they come equipped with extensive documentation and support resources, enhancing the user experience and ensuring efficient integration into existing workflows.

Our commitment to scientific excellence and innovation positions us as a leader in providing high-quality biological products. With a focus on empowering researchers and clinicians, we strive to develop tools that drive advancements in healthcare and biological research, such as the ZNF438 Gene Knockout Cell Lines.

Please note that all services are for research use only. Not intended for any clinical use.

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