Gene: ZNF431
Official Full Name: zinc finger protein 431provided by HGNC
Gene Summary: This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein may negatively regulate transcription of target genes, including the hedgehog signaling pathway receptor patched 1, by interacting with histone deacetylases. Mutations in this gene may be associated with non-syndromic facial clefting in human patients. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12234 | ZNF431 Knockout cell line (HeLa) | Human | ZNF431 | 1:3~1:6 | Negative | Online Inquiry |
KO12235 | ZNF431 Knockout cell line (HCT 116) | Human | ZNF431 | 1:2~1:4 | Negative | Online Inquiry |
KO12236 | ZNF431 Knockout cell line (HEK293) | Human | ZNF431 | 1:3~1:6 | Negative | Online Inquiry |
KO12237 | ZNF431 Knockout cell line (A549) | Human | ZNF431 | 1:3~1:4 | Negative | Online Inquiry |
ZNF431 Gene Knockout Cell Lines represent a cutting-edge biotechnological innovation designed to facilitate advanced research in gene function and regulatory mechanisms. These cell lines are specifically engineered to lack the ZNF431 gene, a critical factor in various biological processes, including development, differentiation, and disease pathways. By providing a controlled environment devoid of this gene, researchers can elucidate its role in cellular functions and its implications in pathological conditions.
The primary mechanism of action for ZNF431 Gene Knockout Cell Lines involves the use of CRISPR/Cas9 technology for precise gene editing. This method allows for the efficient and targeted disruption of the ZNF431 gene, resulting in knockout phenotypes that can be studied further. The resulting cell lines serve as powerful tools for unraveling the complexities associated with gene regulation and the molecular pathways influenced by ZNF431. Their application ranges from fundamental research in molecular biology to translational studies in therapeutic contexts.
In terms of scientific importance, these knockout cell lines are invaluable for researchers investigating cancer biology, neurodegenerative diseases, and other genetic disorders wherein ZNF431 may play a pivotal role. Unlike traditional methods for gene disruption, our ZNF431 Gene Knockout Cell Lines offer higher efficiency and consistency, enabling easier validation of experimental results.
The unique selling points of our product include enhanced reproducibility, straightforward integration into existing experimental protocols, and thorough characterization supporting their use across diverse applications. By utilizing our advanced cell lines, researchers can save time and resources while ensuring reliable data generation—key elements in the competitive landscape of research and development.
Our commitment to excellence in biotechnology is underscored by a seasoned team proficient in genetic engineering and cell biology, ensuring that ZNF431 Gene Knockout Cell Lines stand at the forefront of genomic research tools. As we strive to provide high-quality and reliable biological products, we empower researchers and clinicians to unlock new insights into the molecular basis of health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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