Gene: ZNF416
Official Full Name: zinc finger protein 416provided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in microautophagy; regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within cardiac muscle hypertrophy; negative regulation of cell growth involved in cardiac muscle cell development; and negative regulation of protein phosphorylation. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12250 | ZNF416 Knockout cell line (HeLa) | Human | ZNF416 | 1:3~1:6 | Negative | Online Inquiry |
KO12251 | ZNF416 Knockout cell line (HCT 116) | Human | ZNF416 | 1:2~1:4 | Negative | Online Inquiry |
KO12252 | ZNF416 Knockout cell line (HEK293) | Human | ZNF416 | 1:3~1:6 | Negative | Online Inquiry |
KO12253 | ZNF416 Knockout cell line (A549) | Human | ZNF416 | 1:3~1:4 | Negative | Online Inquiry |
ZNF416 Gene Knockout Cell Lines represent a sophisticated tool for researchers exploring the functional biology of the ZNF416 gene, known to play a crucial role in cellular processes and disease mechanisms. These cell lines have been precisely engineered through CRISPR/Cas9 technology to create targeted disruptions of the ZNF416 gene, allowing for a deeper understanding of its role in gene regulation, cell proliferation, and apoptosis.
The primary mechanism at work in ZNF416 Gene Knockout Cell Lines involves the introduction of specific guide RNAs that direct the Cas9 nuclease to the ZNF416 locus, resulting in double-strand breaks. The cellular repair processes often lead to insertions or deletions (indels) that effectively disrupt the normal gene function, thereby providing researchers with the ability to investigate the biological consequences of ZNF416 knockout in various cellular contexts. This not only enables studies on the gene’s role in homeostasis and response to stress but also allows for the examination of its implications in disease models such as cancer.
The scientific importance of these cell lines extends beyond basic research; they hold significant potential in clinical applications. By elucidating the pathways influenced by the ZNF416 gene, researchers can identify new therapeutic targets and strategies for disease intervention. The use of ZNF416 knockout models may also help in understanding the responsiveness of certain tumors to therapies, laying the groundwork for more personalized approaches to treatment.
What sets our ZNF416 Gene Knockout Cell Lines apart from alternatives is their robust validation and reliability, ensuring reproducibility in experimental designs. Each cell line is rigorously characterized for gene editing efficiency and off-target effects, allowing researchers to trust the outcomes of their studies. Furthermore, our commitment to providing comprehensive technical support and expertise enhances the user experience, ensuring that researchers can effectively harness the full potential of these cell lines in their projects.
Investing in ZNF416 Gene Knockout Cell Lines is more than just acquiring research tools; it is about partnering with a company that thrives on innovation and quality within the realm of genetic engineering. Our expertise and dedication to advancing scientific research empower our clients to make significant strides in their investigations, ultimately contributing to the greater landscape of biomedical science.
Please note that all services are for research use only. Not intended for any clinical use.
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