Gene: ZNF350
Official Full Name: zinc finger protein 350provided by HGNC
Gene Summary: Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Located in nuclear body. Part of transcription repressor complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12289 | ZNF350 Knockout cell line (HeLa) | Human | ZNF350 | 1:3~1:6 | Negative | Online Inquiry |
KO12290 | ZNF350 Knockout cell line (HCT 116) | Human | ZNF350 | 1:2~1:4 | Negative | Online Inquiry |
KO12291 | ZNF350 Knockout cell line (HEK293) | Human | ZNF350 | 1:3~1:6 | Negative | Online Inquiry |
KO12292 | ZNF350 Knockout cell line (A549) | Human | ZNF350 | 1:3~1:4 | Negative | Online Inquiry |
ZNF350 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the ZNF350 gene, a critical regulator of various cellular processes, including transcriptional regulation and signal transduction. This product enables researchers to investigate the functional implications of complete gene loss, providing insight into the biological pathways that ZNF350 influences.
The key function of these knockout cell lines lies in their ability to simulate a complete absence of the ZNF350 gene, thereby allowing researchers to observe the resultant phenotypic and molecular changes. Utilizing CRISPR-Cas9 genome editing technology, these cell lines exhibit a high efficiency of gene disruption, leading to precise and reproducible outcomes. The knockout model is essential for dissecting gene functions and understanding the biological consequences of ZNF350 dysregulation, which has been implicated in various diseases, including cancer and metabolic disorders.
The scientific importance of ZNF350 Gene Knockout Cell Lines extends to both research and clinical settings. In a research context, they serve as invaluable tools for studying gene function and elucidating pathways involved in disease mechanisms. Clinically, these models can aid in drug discovery and development by revealing potential therapeutic targets and evaluating the efficacy of novel treatments.
Compared to traditional cell lines, ZNF350 Gene Knockout Cell Lines offer distinct advantages. They provide a more accurate reflection of in vivo conditions, facilitating more meaningful data collection and analysis. Additionally, their high specificity and reliability make them superior for applications requiring precision, such as high-throughput screening and functional genomics.
For researchers and clinicians striving to unlock the complexities of gene regulation and disease pathology, ZNF350 Gene Knockout Cell Lines provide a crucial resource, driving innovation and discovery. By leveraging the latest advancements in genetic engineering, our company delivers cutting-edge products supported by a commitment to excellence, ensuring that scientists can trust in the quality and reliability of their tools.
Please note that all services are for research use only. Not intended for any clinical use.
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