Gene: ZMYM2
Official Full Name: zinc finger MYM-type containing 2provided by HGNC
Gene Summary: The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO34537 | ZMYM2 Knockout cell line (HeLa) | Human | ZMYM2 | 1:3~1:6 | Negative | Online Inquiry |
KO34538 | ZMYM2 Knockout cell line (HCT 116) | Human | ZMYM2 | 1:2~1:4 | Negative | Online Inquiry |
KO34539 | ZMYM2 Knockout cell line (HEK293) | Human | ZMYM2 | 1:3~1:6 | Negative | Online Inquiry |
KO34540 | ZMYM2 Knockout cell line (A549) | Human | ZMYM2 | 1:3~1:4 | Negative | Online Inquiry |
ZMYM2 Gene Knockout Cell Lines represent an advanced tool for researchers exploring the functional roles of the ZMYM2 gene in various biological processes and disease models. These cell lines have been genetically engineered to specifically delete the ZMYM2 gene, facilitating the study of its involvement in cellular functions, signaling pathways, and potential contributions to cancer progression.
The primary mechanism of the ZMYM2 knockout approach involves CRISPR-Cas9 technology, which allows for targeted deletion of the gene within the cellular genomic DNA. This precise modification results in the ablation of ZMYM2 expression, enabling researchers to assess phenotypic changes, signaling alterations, and gene expression profiles compared to wild-type controls. The presence of these cell lines serves not only to elucidate the biological consequences of ZMYM2 loss but also to investigate potential compensatory mechanisms that may arise in response to its ablation.
The scientific importance of ZMYM2 Gene Knockout Cell Lines lies in their utility for understanding the gene's role in oncogenesis, as well as in developmental and neurological processes. In clinical research, these cell models can further assist in drug screening and therapeutic targeting by providing a platform for testing the efficacy of novel compounds aimed at genes involved in tumorigenesis.
One of the unique advantages of our ZMYM2 Gene Knockout Cell Lines over alternatives is the rigorous validation of gene ablation, ensuring reproducibility and reliability in experimental outcomes. Moreover, these cell lines come with comprehensive characterization data, allowing researchers to confidently interpret their results and make informed decisions in their studies.
Researchers and clinicians will find ZMYM2 Gene Knockout Cell Lines invaluable for deepening their understanding of molecular mechanisms that underpin disease and for accelerating the development of new therapeutic strategies. Our commitment to providing high-quality, genetically modified cell lines, coupled with our extensive expertise in gene editing technologies, positions us as a leading provider of essential tools for biomedical research. By choosing our products, you are equipping yourself with the best resources to propel your research forward.
Please note that all services are for research use only. Not intended for any clinical use.
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