Gene: ZC3H12B
Official Full Name: zinc finger CCCH-type containing 12Bprovided by HGNC
Gene Summary: The protein encoded by this gene belongs to a family of CCCH-type zinc finger proteins that are involved in the proinflammatory activation of macrophages. The exact function of this family member is unknown, but it is thought to function as a ribonuclease. [provided by RefSeq, May 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12467 | ZC3H12B Knockout cell line (HCT 116) | Human | ZC3H12B | 1:2~1:4 | Negative | Online Inquiry |
KO12468 | ZC3H12B Knockout cell line (HEK293) | Human | ZC3H12B | 1:3~1:6 | Negative | Online Inquiry |
ZC3H12B Gene Knockout Cell Lines are genetically modified cellular models that have been created to specifically lack the expression of the ZC3H12B gene. This gene plays a crucial role in the regulation of immune responses, particularly in the context of inflammatory processes and hematopoiesis. The knockout of ZC3H12B allows researchers to investigate its function and the subsequent alterations in cellular pathways that influence various biological responses, making it an invaluable tool for studying gene function and mechanisms of disease.
These cell lines operate based on the principle of gene editing through CRISPR/Cas9 technology or similar techniques, resulting in precise deletions or modifications of the ZC3H12B gene. By utilizing these knockout models, scientists can effectively dissect the molecular pathways regulated by ZC3H12B, providing insights into its role in diseases such as autoimmune disorders and certain types of cancers. This has significant implications for both basic research and the development of targeted therapies.
In research and clinical environments, ZC3H12B Gene Knockout Cell Lines serve as critical assets for understanding the complexities of immune modulation and potential therapeutic interventions. Their ability to replicate human disease states makes them instrumental in drug discovery and personalized medicine strategies.
One of the distinct advantages of these knockout cell lines is their specificity; they provide an unambiguous model to study the consequences of abolishing ZC3H12B function without confounding effects from other genes. This specificity can lead to clearer insights and more reliable data compared to alternative models that may not fully recapitulate the gene's effects.
For researchers and clinicians focused on immunology, hematology, or cancer biology, investing in ZC3H12B Gene Knockout Cell Lines represents a strategic choice. They not only facilitate robust experimental designs but also enhance the reproducibility of findings critical for advancing scientific knowledge and therapeutic development.
Our company prides itself on delivering high-quality biological products backed by extensive expertise in genetic engineering and cell biology. We are committed to supporting the scientific community with innovative solutions that empower researchers to make groundbreaking discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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