Gene: ZBTB7C
Official Full Name: zinc finger and BTB domain containing 7Cprovided by HGNC
Gene Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of cell population proliferation. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO37314 | ZBTB7C Knockout cell line (HeLa) | Human | ZBTB7C | 1:3~1:6 | Negative | Online Inquiry |
KO37315 | ZBTB7C Knockout cell line (HEK293) | Human | ZBTB7C | 1:3~1:6 | Negative | Online Inquiry |
ZBTB7C gene knockout cell lines are specifically engineered cellular systems designed to functionally study the role of the ZBTB7C gene, which encodes a transcription factor involved in critical biological processes such as immune response regulation and cellular differentiation. By employing CRISPR/Cas9 gene editing technology, these knockout cell lines provide researchers with a precise tool to explore the gene's pathways and its implications in various physiological and pathological contexts.
The primary mechanism of action involves the intentional disruption of the ZBTB7C gene, effectively eliminating its expression within the cell lines. This results in the ability to observe and quantify changes in cellular behavior, gene expression profiles, and response to external stimuli, allowing researchers to elucidate the functional consequences of ZBTB7C loss in vitro. This knockout model is particularly valuable in studying its roles in various fields, from immunology and oncology to developmental biology, offering insights into how dysregulation of ZBTB7C may contribute to diseases such as leukemia or autoimmune disorders.
The scientific importance of ZBTB7C knockout cell lines is underscored by their potential applications in drug discovery, biomarker identification, and the development of novel therapeutic strategies. Unlike traditional models, these cell lines provide a more relevant biological context, enhancing the translatability of findings to clinical settings. Additionally, specific advantages include high reproducibility and easy integration into high-throughput screening assays, enabling researchers to conduct extensive analyses efficiently.
What sets ZBTB7C gene knockout cell lines apart from alternatives is their robust validation and characterization, providing confidence in the data obtained. They represent a fundamental breakthrough for scientists looking to rigorously investigate gene function and therapeutic targets.
Our company is dedicated to advancing the life sciences through innovative solutions, supported by extensive expertise in genetic engineering and cell line development. By offering high-quality ZBTB7C gene knockout cell lines, we empower researchers and clinicians to deepen their understanding of complex biological mechanisms and translate these insights into tangible health advancements.
Please note that all services are for research use only. Not intended for any clinical use.
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