Gene: VTA1
Official Full Name: vesicle trafficking 1provided by HGNC
Gene Summary: C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).[supplied by OMIM, Mar 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO22421 | VTA1 Knockout cell line (HeLa) | Human | VTA1 | 1:3~1:6 | Negative | Online Inquiry |
KO22422 | VTA1 Knockout cell line (HCT 116) | Human | VTA1 | 1:2~1:4 | Negative | Online Inquiry |
KO22423 | VTA1 Knockout cell line (HEK293) | Human | VTA1 | 1:3~1:6 | Negative | Online Inquiry |
KO22424 | VTA1 Knockout cell line (A549) | Human | VTA1 | 1:3~1:4 | Negative | Online Inquiry |
VTA1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the expression of the VTA1 gene, a critical component involved in vesicular transport processes and cellular signaling pathways. By utilizing CRISPR-Cas9 gene editing technology, these cell lines allow researchers to explore the specific roles of VTA1 in various biological functions, including membrane trafficking, protein sorting, and cellular stress responses. The elimination of VTA1 enables a clearer understanding of its impact on cellular homeostasis and provides insights into its potential association with various diseases.
The key function of these knockout cell lines lies in their ability to serve as a controlled environment for investigations into the downstream effects of VTA1 deficiency. Researchers can employ these models to study altered cellular behaviors, signaling cascades, and gene expression profiles, thereby elucidating the mechanisms by which VTA1 influences cellular physiology and pathology. Moreover, these cell lines are invaluable in drug discovery and development, allowing scientists to identify potential therapeutic targets for conditions linked to VTA1 dysregulation.
Compared to other gene knockout models, VTA1 Gene Knockout Cell Lines offer unique advantages in specificity and reliability. These models help circumvent compensatory mechanisms often encountered in whole-organism studies, providing more accurate and reproducible data. Their ease of use in culture systems accelerates experimental timelines and enhances the feasibility of high-throughput screening applications.
For researchers and clinicians focused on the mechanistic aspects of cellular transport systems and their implications in health and disease, the VTA1 Gene Knockout Cell Lines represent an essential tool. These cell lines not only support cutting-edge scientific inquiries but also facilitate the translation of basic research into clinical applications. Our company prides itself on delivering high-quality biological products backed by years of expertise, ensuring that our VTA1 Gene Knockout Cell Lines contribute significantly to advancing the frontiers of biomedical research.
Please note that all services are for research use only. Not intended for any clinical use.
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