Gene: VCPKMT
Official Full Name: valosin containing protein lysine methyltransferaseprovided by HGNC
Gene Summary: Enables ATPase binding activity and protein-lysine N-methyltransferase activity. Involved in negative regulation of ATP-dependent activity and peptidyl-lysine trimethylation. Located in cytosol. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO12694 | VCPKMT Knockout cell line (HeLa) | Human | VCPKMT | 1:3~1:6 | Negative | Online Inquiry |
KO12695 | VCPKMT Knockout cell line (HCT 116) | Human | VCPKMT | 1:2~1:4 | Negative | Online Inquiry |
KO12696 | VCPKMT Knockout cell line (HEK293) | Human | VCPKMT | 1:3~1:6 | Negative | Online Inquiry |
KO12697 | VCPKMT Knockout cell line (A549) | Human | VCPKMT | 1:3~1:4 | Negative | Online Inquiry |
VCPKMT Gene Knockout Cell Lines are specially engineered cell lines that have undergone targeted gene knockout of the VCPKMT gene, which encodes the enzyme vimpatine coenzyme A methyltransferase, a key player in cellular processes such as protein degradation and mitochondrial function. These knockout lines facilitate in-depth investigation into the specific roles of VCPKMT, offering researchers a powerful tool for studying its influence on cellular metabolism, stress responses, and the pathogenesis of diseases such as cancer and neurodegeneration.
The key function of VCPKMT Gene Knockout Cell Lines lies in their ability to elucidate the molecular mechanisms by which VCPKMT contributes to cellular homeostasis and disease progression. By creating a context where VCPKMT is rendered non-functional, researchers can dissect downstream signaling pathways affected by this loss, providing insight into protein degradation pathways and mitochondrial integrity under stress conditions.
In research and clinical settings, these knockout cell lines are invaluable for drug discovery, biomarker identification, and pathway elucidation. They allow for the assessment of potential therapeutic targets and the evaluation of drug efficacy against diseases linked to aberrant VCPKMT activity.
What sets VCPKMT Gene Knockout Cell Lines apart from alternative models is their high specificity and reliability, enabling reproducible results across various study designs. Moreover, they are developed using the latest CRISPR/Cas9 gene-editing technology, ensuring precision in genetic alteration while preserving other aspects of the cellular phenotype.
For researchers and clinicians, the value of VCPKMT Gene Knockout Cell Lines cannot be overstated. These cell lines not only streamline experimental workflows but also provide robust data that can drive discoveries in molecular biology and personalized medicine.
With a commitment to excellence in biological product development, our company brings years of expertise and innovation, ensuring that our offerings, including VCPKMT Gene Knockout Cell Lines, meet the highest standards of quality and scientific integrity to further propel your research initiatives.
Please note that all services are for research use only. Not intended for any clinical use.
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