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UBTD1 Knockout Cell Lines

Gene: UBTD1

Official Full Name: ubiquitin domain containing 1provided by HGNC

Gene Summary: The degradation of many proteins is carried out by the ubiquitin pathway in which proteins are targeted for degradation by covalent conjugation of the polypeptide ubiquitin. This gene encodes a protein that belongs to the ubiquitin family of proteins. The encoded protein is thought to regulate E2 ubiquitin conjugating enzymes belonging to the UBE2D family. [provided by RefSeq, Mar 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO26299 UBTD1 Knockout cell line (HeLa) Human UBTD1 1:3~1:6 Negative Online Inquiry
KO26300 UBTD1 Knockout cell line (HCT 116) Human UBTD1 1:2~1:4 Negative Online Inquiry
KO26301 UBTD1 Knockout cell line (HEK293) Human UBTD1 1:3~1:6 Negative Online Inquiry
KO26302 UBTD1 Knockout cell line (A549) Human UBTD1 1:3~1:4 Negative Online Inquiry

Background

UBTD1 Gene Knockout Cell Lines are engineered cellular models specifically designed to investigate the role of the UBTD1 (ubiquitin T-like domain-containing protein 1) gene in various biological processes. These cell lines have been meticulously developed through CRISPR/Cas9 technology, resulting in a complete ablation of UBTD1 expression. This knockout model provides invaluable insights into the functions of UBTD1, which is implicated in several cellular mechanisms, including regulation of protein degradation, cellular stress responses, and modulation of inflammation pathways.

The primary mechanism of action for UBTD1 involves its interaction with ubiquitin, a key player in post-translational modification and proteasomal degradation of proteins. By utilizing our UBTD1 Gene Knockout Cell Lines, researchers can systematically explore how the absence of UBTD1 affects cellular homeostasis, signaling cascades, and pathophysiological conditions, thereby uncovering critical insights relevant to cancer biology, neurodegenerative diseases, and immune responses.

The scientific importance of these cell lines is underscored by their potential applications in both research and clinical settings. They serve as essential tools for validating targets for therapeutic intervention through high-throughput screening of potential drug candidates, elucidating the mechanisms of disease, and even advancing gene therapy approaches.

Compared to traditional models, the UBTD1 Gene Knockout Cell Lines offer several unique advantages, including high fidelity in gene editing, reproducibility across experiments, and the ability to easily integrate with functional assays. This ensures that researchers can conduct more rigorous and meaningful studies while reducing variability that often hampers results in standard models.

The value of UBTD1 Gene Knockout Cell Lines extends beyond their immediate applications; they empower researchers and clinicians to expand their inquiries into complex cellular dynamics with precision, ultimately leading to enhanced understanding and potential breakthroughs in therapeutics.

At [Company Name], we have a strong commitment to advancing biological research. Our expertise in next-generation genetic modification and cell line generation assures you are working with high-quality tools designed to facilitate groundbreaking discoveries in your laboratory or clinical setting.

Please note that all services are for research use only. Not intended for any clinical use.

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