Gene: UBIAD1
Official Full Name: UbiA prenyltransferase domain containing 1provided by HGNC
Gene Summary: This gene encodes a protein thought to be involved in cholesterol and phospholipid metabolism. Mutations in this gene are associated with Schnyder crystalline corneal dystrophy. [provided by RefSeq, Oct 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26956 | UBIAD1 Knockout cell line (HeLa) | Human | UBIAD1 | 1:3~1:6 | Negative | Online Inquiry |
KO26957 | UBIAD1 Knockout cell line (HCT 116) | Human | UBIAD1 | 1:2~1:4 | Negative | Online Inquiry |
KO26958 | UBIAD1 Knockout cell line (HEK293) | Human | UBIAD1 | 1:3~1:6 | Negative | Online Inquiry |
KO26959 | UBIAD1 Knockout cell line (A549) | Human | UBIAD1 | 1:3~1:4 | Negative | Online Inquiry |
UBIAD1 Gene Knockout Cell Lines are specifically engineered cellular models that possess a targeted disruption of the UBIAD1 gene, which encodes a protein involved in the synthesis of ubiquinone (CoQ10) and has implications in various biological processes, including mitochondrial function and cell signaling. These knockout cell lines allow researchers to study the effects of UBIAD1 deficiency in a controlled environment, enabling the elucidation of its role in cellular metabolism, oxidative stress responses, and potential contributions to diseases associated with mitochondrial dysfunction.
Functionally, these cell lines function as powerful tools for exploring the downstream effects that arise from UBIAD1 gene disruption. The absence of the UBIAD1 protein leads to a decrease in ubiquinone levels, impairing electron transport in mitochondria and impacting ATP production. This model system facilitates in-depth investigations into metabolic pathways, the assessment of cellular viability, and the understanding of possible therapeutic interventions for disorders such as neurodegenerative diseases and certain cancers.
The scientific importance of UBIAD1 Gene Knockout Cell Lines cannot be overstated. They are pivotal in research settings aimed at dissecting the molecular mechanisms of diseases and testing the efficacy of potential pharmacological agents that target mitochondrial dysfunction. Moreover, these models have significant applications in drug discovery processes, as they provide critical insights into drug metabolism and therapeutic efficacy.
What sets UBIAD1 Gene Knockout Cell Lines apart from alternative models is their specificity and reliability. Unlike nonspecific gene disruption methods, our knockout cell lines ensure precise gene targeting, which enhances reproducibility and the validity of experimental outcomes. Additionally, the use of robust screening techniques ensures minimal off-target effects, making findings derived from these models more trustworthy and applicable to translational research.
For researchers and clinicians focused on mitochondrial biology and its related pathologies, UBIAD1 Gene Knockout Cell Lines present a unique avenue for advancing scientific knowledge and therapeutic strategies. Our commitment to quality and precision in biotechnological development is reflected in these products, ensuring that users are well-equipped with the necessary tools for groundbreaking research and clinical advancements.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.